Forkhead box protein I1 Antibodies

Forkhead box protein I1 (FOXI1)

Transcriptional activator required for the progression of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear.

Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules (By similarity). .

Gene Information

Human
Gene Name:	FOXI1
Uniprot:	Q12951
Entrez:	2299

Family

Belongs to:
No superfamily

Alternative Names

FKHL10HFH3; forkhead box I1; forkhead box protein I1; forkhead-like 10; forkhead-related activator 6; Forkhead-related protein FKHL10; Forkhead-related transcription factor 6; FREAC-6; FREAC6FKH10; Hepatocyte nuclear factor 3 forkhead homolog 3; HFH-3; HNF-3/fork-head homolog 3; HNF-3/fork-head homolog-3; MGC34197

Molecular Weight

Mass (kDA):
40.973 kDA

Genomic Context

Human
Location:	5q35.1
Sequence:	5; NC_000005.10 (170105897..170109734)

Tissue Specificity

Expressed in kidney.

Subcellular Localizations

Nucleus.

Diseases

• Pendred's Syndrome
• Sensorineural Hearing Loss (disorder)
• Acidosis
• Renal Tubular Acidosis
• Complete Hearing Loss
• Crest Syndrome
• Nodular Goiter
• Renal Tubular Acidosis, Type I
• Nervousness
• Dysplasia
• Neoplasms
• Trematode Infections
• Liver Carcinoma

• Congenital Ear Anomaly Nos (disorder)
• Pathological Dilatation
• Hypertensive Disease
• Essential Hypertension
• Disease Of Adrenal Medulla
• Jaw Abnormalities
• Respirovirus Infections

Interacting Proteins

• VPS37C

Pathways

• Gastrulation
• Cell Differentiation
• Ear Development
• Transport
• Neurogenesis
• Inner Ear Development
• Epithelial Cell Differentiation
• Cell Death
• Cell Fate Determination
• Otic Placode Formation
• Ion Transport
• Regeneration
• Pathogenesis

• Cell Migration
• Neural Crest Cell Migration
• Developmental Process
• Fertilization
• Lung Development
• Hypersensitivity
• Sweat Gland Development

PTMs

• Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FOXI1

Boster Bio - Best Uses Of The FOXI1 Marker

Boster Bio can use Forkheadbox protein E1 to generate transcription factors. However, you need to know a few things about the forkhead box protein E1 marker. Here are some tips to optimize your experiment. Boster Bio offers many flow procedures that you can choose from. The flow procedure you choose should be in line with your experiment's goals.

Forkhead box protein E1

Forkhead protein E1 is inhibited from producing ROS, and promotes the production FOXN1 and SOD. Both of these enzymes are important for maintaining healthy blood levels. But what about the effect of thiostrepton upon FoxM1's expression? Its mechanism of action is currently unknown, but it is thought to regulate tumor progression.

Boster Bio optimization Tips

These Boster bio optimization tips can help you optimize your experiments using the FOXI1 mark. The informationgraphics about each gene give basic information. You can search for specific genes by using the gene search tool. If you are not familiar with this gene, you can also use the Boster Bio search bar to look up relevant information. There are many flow options.

Forkhead protein E1 is a transcription factor

Forkhead box protein (E1) is a member in the FOX family. It is essential for cell-cycle progression. It is produced by the thymic cells of the epithelial cells. It plays an important role within many cellular processes. Boster Bio uses the protein to develop antibodies to detect its presence in animal samples. This gene may indirectly regulate cell growth and migration through the WNT5A gene.