FLVCR2 Antibodies

AND FLVCR2 ELISA kits, FLVCR2 Proteins

Many biological assays use antibodies to detect FLVCR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FLVCR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FLVCR2 antibodies...

We validate the specificity of these antibodies to FLVCR2 by testing them on tissues known to express FLVCR2 positively and negatively. Browse below to find the FLVCR2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FLVCR2 Infographic by Boster Bio

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FLVCR2 (NM_017791) Human Recombinant Protein

$813
Cat # PROTQ9UPI3
20 µg

FLVCR2 Overview

Facts about Feline leukemia virus subgroup C receptor-related protein 2.

FLVCR2 3D structure. Source: alphafold

Feline leukemia virus subgroup C receptor-related protein 2 (FLVCR2)

Acts as an importer of heme.
Also acts as a transporter for a calcium-chelator complicated, important for growth and calcium metabolism.

Gene Information

Human
Gene Name:	FLVCR2
Uniprot:	Q9UPI3
Entrez:	55640

Family

Belongs to:

major facilitator superfamily

Alternative Names

feline leukemia virus subgroup C cellular receptor family, member 2

Molecular Weight

Mass (kDA):
57.241 kDA

Genomic Context


Human

Location:	14q24.3
Sequence:	14; NC_000014.9 (75578620..75648167)

Tissue Specificity

Expressed in non-hematopoietic tissues, with relative abundant expression in brain, placenta, lung, liver and kidney. Also expressed in hematopoietic tissues (fetal liver, spleen, lymph node, thymus, leukocytes and bone marrow). Found in acidophil cells of the pituitary that secrete growth hormone and prolactin.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Leukemia, Feline
Leukemia
Vascular Diseases
Hydrocephalus
Hydranencephaly
Brain Diseases
Malnutrition
Ischemia
Atrophy
Tumor Angiogenesis

Pena-shokeir Syndrome Type I
Nervousness
Cerebrovascular Accident
Pathologic Neovascularization

Pathways

Response To Ischemia
Regulation Of Growth
Angiogenesis

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FLVCR2

References

PMID: 14729055 by Brasier G., et al. Novel hexad repeats conserved in a putative transporter with restricted expression in cell types associated with growth, calcium exchange and homeostasis.

PMID: 20823265 by Duffy S.P., et al. The Fowler syndrome-associated protein FLVCR2 is an importer of heme.