FLRT1 Antibodies

AND FLRT1 ELISA kits, FLRT1 Proteins

Many biological assays use antibodies to detect FLRT1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FLRT1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FLRT1 antibodies...

We validate the specificity of these antibodies to FLRT1 by testing them on tissues known to express FLRT1 positively and negatively. Browse below to find the FLRT1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FLRT1 Infographic by Boster Bio

All FLRT1 Products

Product

Figures

Specificity

Applications

Price

Anti-FLRT1 Antibody

Human

ELISA, WB

$380
Cat # A12756
100ul

FLRT1 (NM_013280) Human Recombinant Protein

$1249
Cat # PROTQ9NZU1
20 µg

FLRT1 (NM_013280) Human Over-expression Lysate

Human

$628
Cat # LS023769
100 µg

FLRT1 Overview

Facts about Leucine-rich repeat transmembrane protein FLRT1.

FLRT1 3D structure. Source: alphafold

Leucine-rich repeat transmembrane protein FLRT1 (FLRT1)

Plays a role in fibroblast growth factor-mediated signaling cascades that result in the activation of MAP kinases. Promotes neurite outgrowth through FGFR1-mediated activation of downstream MAP kinases.

Promotes an increase both in neurite number and in neurite length. May play a role in cell-cell adhesion and cell guidance via its interaction with ADGRL1/LPHN1 and ADGRL3.

Gene Information

Human
Gene Name:	FLRT1
Uniprot:	Q9NZU1
Entrez:	23769

Family

Belongs to:

No superfamily

Alternative Names

fibronectin leucine rich transmembrane protein 1; Fibronectin-like domain-containing leucine-rich transmembrane protein 1; FLRT1; leucine-rich repeat transmembrane protein FLRT1; MGC21624; SPG68

Molecular Weight

Mass (kDA):
71.358 kDA

Genomic Context


Human

Location:	11q13.1
Sequence:	11; NC_000011.10 (64035970..64127289)

Tissue Specificity

Expressed in kidney and brain.

Subcellular Localizations

Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane. Cytoplasmic vesicle membrane. Cytoplasm, perinuclear region. Cell junction, focal adhesion. Secreted. Cell projection, neuron projection. Cell junction. In addition to its location at the cell membrane, colocalizes with FGFR1 in punctate perinuclear cytoplasmic vesicles. Detected along neurites and at contacts between neurite termini and other cells. Proteolytic cleavage gives rise to a shedded ectodomain.

Diseases

Tissue Adhesions
Neuroblastoma
Nervousness

Pathways

Cell Adhesion
Gastrulation
Primitive Streak Formation
Neuron Migration
System Development
Tissue Morphogenesis
Axon Guidance
Nervous System Development

Localization
Somite Development

PTMs

Glycosylation

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FLRT1

References

PMID: 10644439 by Lacy S.E., et al. Identification of FLRT1, FLRT2, and FLRT3: a novel family of transmembrane leucine-rich repeat proteins.