Ffar4 Antibodies

AND Ffar4 ELISA kits, Ffar4 Proteins

Many biological assays use antibodies to detect Ffar4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ffar4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ffar4 antibodies...

We validate the specificity of these antibodies to Ffar4 by testing them on tissues known to express Ffar4 positively and negatively. Browse below to find the Ffar4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Ffar4 Infographic by Boster Bio

All Ffar4 Products

Product

Figures

Specificity

Applications

Price

Anti-GPR120 FFAR4 Antibody

12 Q&As

Human, Mouse, Rat

$399
Cat # A04709
100μl

Anti-GPR120 FFAR4 Antibody

1 Citations 1 Q&As

Human, Mouse, Rat

ELISA, IF, ICC, WB

$335
Cat # A19859
100ul

Ffar4 Overview

Facts about Free fatty acid receptor 4.

Free fatty acid receptor 4 (Ffar4)

Receptor for moderate and long-chain free fatty acids (FFAs). Signals via a G(q)/G(11)-coupled pathway.

Acts as a receptor for omega-3 fatty acids and mediates robust anti- inflammatory effects, particularly in macrophages and fat cells. The anti-inflammatory effects include inhibition of TAK1 by means of a beta-arrestin 2 (ARRB2)/TAB1-dependent effect, but independent of the G(q)/G(11)-coupled pathway.

Gene Information

Mouse
Gene Name:	Ffar4
Uniprot:	Q7TMA4
Entrez:	107221

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

FFAR4; G protein-coupled receptor 120; G protein-coupled receptor 129; G protein-coupled receptor PGR4; GPR120; GPR129; G-protein coupled receptor 120; G-protein coupled receptor 129; G-protein coupled receptor GT01; G-protein coupled receptor PGR4; G-protein-coupled receptor GT01; GT01; MGC119984; O3FAR1; omega-3 fatty acid receptor 1; PGR4; PGR4DKFZp686F0824

Molecular Weight

Mass (kDA):
40.813 kDA

Genomic Context


Mouse

Location:	19\|19 C2
Sequence:	19;

Tissue Specificity

Expressed in the taste buds of the circumvallate and fungiform papillae, mainly in type II cells (at protein level). Abundant expression in the intestinal tract. Highly expressed in adipose tissue, including subcutaneous, perineral, mesentric and epididymal adipose tissue. Expressed in proinflammatory CD11c+ macrophages, mature adipocytes, RAW 264.7 cells and enteroendocrine L cells. Expressed in the epithelium of circumvallate papillae containing taste buds but not in the nonsensory lingual epithelium. High expression detected also in pituitary gland, lung and spleen. Negligible expression in muscle, liver, brain, heart, kidney and stomach.

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Ffar4

References

PMID: 14623098 by Fredriksson R., et al. Seven evolutionarily conserved human rhodopsin G protein-coupled receptors lacking close relatives.

PMID: 15619630 by Hirasawa A., et al. Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120.

1 Publications of Boster Ffar4 Antibodies & ELISA Kits

PubMed ID: 10.1152/ajpendo.00509.2019, Targeting FFA1 and FFA4 receptors in cancer-induced cachexia

*More publications can be found for each product on its corresponding product page