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Facts about Adrenodoxin, mitochondrial.
Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage (PubMed:20547883, PubMed:21636783). Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity).
Human | |
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Gene Name: | FDX1 |
Uniprot: | P10109 |
Entrez: | 2230 |
Belongs to: |
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adrenodoxin/putidaredoxin family |
Adrenal ferredoxin; adrenodoxin, mitochondrial; ADXhepatoredoxin; FDX; ferredoxin 1; ferredoxin-1; Hepatoredoxin; LOH11CR1D; mitochondrial adrenodoxin
Mass (kDA):
19.393 kDA
Human | |
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Location: | 11q22.3 |
Sequence: | 11; NC_000011.10 (110429948..110464884) |
Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).
Mitochondrion matrix.
PMID: 3229285 by Chang C.-Y., et al. Cloning and structure of the human adrenodoxin gene.
PMID: 3343244 by Picado-Leonard J., et al. Human adrenodoxin: cloning of three cDNAs and cycloheximide enhancement in JEG-3 cells.