FDXR Antibodies

AND FDXR ELISA kits, FDXR Proteins

Many biological assays use antibodies to detect FDXR, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FDXR in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FDXR antibodies...

We validate the specificity of these antibodies to FDXR by testing them on tissues known to express FDXR positively and negatively. Browse below to find the FDXR antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FDXR Infographic by Boster Bio

All FDXR Products

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Specificity

Applications

Price

Anti-FDXR Antibody

Human, Mouse, Rat

$405
Cat # A06933
100ul

Ferredoxin Reductase (FDXR) (NM_024417) Human Recombinant Protein

$813
Cat # PROTP22570
20 µg

Ferredoxin Reductase (FDXR) (NM_024417) Human Over-expression Lysate

Human

$628
Cat # LS002232
100 µg

FDXR Overview

Facts about NADPH:adrenodoxin oxidoreductase, mitochondrial.

FDXR 3D structure. Source: alphafold

NADPH:adrenodoxin oxidoreductase, mitochondrial (FDXR)

Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal gland, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. .

Gene Information

Human
Gene Name:	FDXR
Uniprot:	P22570
Entrez:	2232

Family

Belongs to:

ferredoxin--NADP reductase type 1 family

Alternative Names

Adrenodoxin reductase; ADXREC 1.18.1.2; ferredoxin reductaseAR; Ferredoxin--NADP(+) reductase; NADPH:adrenodoxin oxidoreductase, mitochondrial

Molecular Weight

Mass (kDA):
53.837 kDA

Genomic Context


Human

Location:	17q25.1
Sequence:	17; NC_000017.11 (74862497..74872994, complement)

Subcellular Localizations

Mitochondrion inner membrane; Peripheral membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Colorectal Neoplasms
Colorectal Cancer
Cell Transformation, Neoplastic
Melanoma
Malignant Tumor Of Colon
Carcinoma
Malignant Paraganglionic Neoplasm
Inflammation
Radiation Injury
Instabilities, Chromosomal

Neoplasm Metastasis
Embryonal Carcinoma
Malignant Neoplasm Of Breast
Neoplasms, Germ Cell And Embryonal
Fibrosis
Chronic Kidney Disease
Mammary Neoplasms

Pathways

Cell Cycle
Localization
Cell Proliferation
Dna Repair
Cell Cycle Arrest
Cell Death
Response To Radiation
Pathogenesis
Transport
Regulation Of Cell Cycle
Programmed Cell Death
Cell Killing

Hypersensitivity
Response To 5-fluorouracil
Reverse Transcription
Response To Uv
Embryo Implantation
Cell Growth
Iron-sulfur Cluster Assembly

PTMs

Reduction

Phosphorylation

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FDXR

References

PMID: 2845396 by Solish S.B., et al. Human adrenodoxin reductase: two mRNAs encoded by a single gene on chromosome 17cen-->q25 are expressed in steroidogenic tissues.

PMID: 2236061 by Lin D., et al. Cloning and sequence of the human adrenodoxin reductase gene.