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- Table of Contents
Facts about Squalene synthase.
Human | |
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Gene Name: | FDFT1 |
Uniprot: | P37268 |
Entrez: | 2222 |
Belongs to: |
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phytoene/squalene synthase family |
DGPT; EC 2.5.1.21; ERG9; farnesyl-diphosphate farnesyltransferase 1; Farnesyl-diphosphate farnesyltransferase; FPP:FPP farnesyltransferase; presqualene-di-diphosphate synthase; SQS; squalene synthase; squalene synthetase; SS
Mass (kDA):
48.115 kDA
Human | |
---|---|
Location: | 8p23.1 |
Sequence: | 8; NC_000008.11 (11795573..11839309) |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
PMID: 8474436 by Robinson G.W., et al. Conservation between human and fungal squalene synthetases: similarities in structure, function, and regulation.
PMID: 7685352 by Jiang G., et al. Transcriptional regulation by lovastatin and 25-hydroxycholesterol in HepG2 cells and molecular cloning and expression of the cDNA for the human hepatic squalene synthase.