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- Table of Contents
Facts about Fc receptor-like protein 2.
Human | |
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Gene Name: | FCRL2 |
Uniprot: | Q96LA5 |
Entrez: | 79368 |
Belongs to: |
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No superfamily |
CD307b antigen; CD307b; Fc receptor homolog 2; Fc receptor-like 2; FcRH2; FCRH2SPAP1B; FCRL2; FcR-like protein 2; IFGP family protein 4; IFGP4; Immunoglobulin receptor translocation-associated protein 4; immunoglobulin superfamily Fc receptor, gp42; IRTA4; IRTA4SPAP1C; SH2 domain containing phosphatase anchor protein 1; SH2 domain-containing phosphatase anchor protein 1Fc receptor-like protein 2; SPAP1; SPAP1A; SPAP1immune receptor translocation-associated protein 4
Mass (kDA):
55.542 kDA
Human | |
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Location: | 1q23.1 |
Sequence: | 1; NC_000001.11 (157745733..157777472, complement) |
Expressed in the secondary lymphoid organs, spleen and lymph node. Expression is limited to the mature B-cell lines. Highly expressed in CD19 and within the mantle zones of the tonsil tissue. Isoform 2 is expressed in the spleen, peripheral blood and bone marrow. Isoform 2 and isoform 4 are expressed in B- cell lines. Preferentially expressed in memory B-cells (at protein level).
Cell membrane; Single-pass type I membrane protein.
PMID: 11493702 by Davis R.S., et al. Identification of a family of Fc receptor homologs with preferential B cell expression.
PMID: 11162587 by Xu M.-J., et al. Molecular cloning and characterization of SPAP1, an inhibitory receptor.