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Ficolin-2 Antibodies
AND FCN2 ELISA kits, Ficolin-2 Proteins
Many biological assays use antibodies to detect Ficolin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ficolin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ficolin-2 antibodies...
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FCN2 Infographic by Boster Bio
All FCN2 Products
Product
Figures
Specificity
Applications
Price
Human
ELISA
$450
Cat # EK1258
96 wells/kit, with removable strips.
Cat # EK1258
96 wells/kit, with removable strips.
FCN2 Overview
Facts about Ficolin-2.
Ficolin-2 (FCN2)
May function in innate immunity during activation of the lectin complement pathway. Calcium-dependent and GlcNAc- binding lectin.
Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect through the collagen region.
Gene Information
| Human | |
|---|---|
| Gene Name: | FCN2 |
| Uniprot: | Q15485 |
| Entrez: | 2220 |
Family
| Belongs to: |
|---|
| ficolin lectin family |
Alternative Names
37 kDa elastin-binding protein; Collagen/fibrinogen domain-containing protein 2; EBP-37ficolin (collagen/fibrinogen domain-containing lectin) 2 (hucolin); FCN2; FCNL; FCNLficolin B; ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin); Ficolin2; Ficolin-2; ficolin-B; ficolin-beta; Hucolin; L-Ficolin; P35; Serum lectin p35
Molecular Weight
Mass (kDA):
34.001 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9q34.3 |
| Sequence: | 9; NC_000009.12 (134864062..134890506) |
Tissue Specificity
Expressed by the liver and secreted in plasma.
Subcellular Localizations
Secreted.
Diseases
- Infective Disorder
- Communicable Diseases
- Malaria
- Respiratory Tract Infections
- Hepatitis B
- Dysequilibrium Syndrome
- Schistosomiasis
- Hepatitis
- Leprosy
- Pneumococcal Infections
- Pneumonia
- Delayed Graft Function
- Behcet Syndrome
Interacting Proteins
- LRP1
- PTX3
Pathways
- Complement Activation
- Immune Response
- Pathogenesis
- Phagocytosis
- Coagulation
- Innate Immune Response
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FCN2
bosterbio.com/bosterbio-gene-info-cards/FCN2
References
PMID: 8884275 by Endo Y., et al. Cloning and characterization of the human lectin P35 gene and its related gene.
PMID: 8576206 by Matsushita M., et al. A novel human serum lectin with collagen- and fibrinogen-like domains that functions as an opsonin.