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- Table of Contents
Facts about High affinity immunoglobulin epsilon receptor subunit alpha.
Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE contributes to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy.
Human | |
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Gene Name: | FCER1A |
Uniprot: | P12319 |
Entrez: | 2205 |
Belongs to: |
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No superfamily |
Fc epsilon RI alpha; FCE1A; FCER1A; FcERI; FceRIa
Mass (kDA):
29.596 kDA
Human | |
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Location: | 1q23.2 |
Sequence: | 1; NC_000001.11 (159283888..159308224) |
Cell membrane; Single-pass type I membrane protein.
PMID: 2967464 by Kochan J., et al. Isolation of the gene coding for the alpha subunit of the human high affinity IgE receptor.
PMID: 2964640 by Shimizu A., et al. Human and rat mast cell high-affinity immunoglobulin E receptors: characterization of putative alpha-chain gene products.