Fibulin-1 Antibodies

AND FBLN1 ELISA kits, Fibulin-1 Proteins

Many biological assays use antibodies to detect Fibulin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Fibulin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Fibulin-1 antibodies...

We validate the specificity of these antibodies to Fibulin-1 by testing them on tissues known to express FBLN1 positively and negatively. Browse below to find the FBLN1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FBLN1 Infographic by Boster Bio

All FBLN1 Products

Product

Figures

Specificity

Applications

Price

Anti-Fibulin-1 FBLN1 Antibody

Human, Mouse, Rat

$405
Cat # A02970
100ul

Anti-Fibulin 1/FBLN1 Antibody Picoband™

Human

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A02970-1
100 μg/vial

Fibulin 1 (FBLN1) (NM_006486) Human Over-expression Lysate

Human

$960
Cat # LS002192
100 µg

FBLN1 Overview

Facts about Fibulin-1.

FBLN1 3D structure. Source: alphafold

Fibulin-1 (FBLN1)

Integrated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM).

Could be significant for specific developmental processes and bring about the supramolecular organization of ECM architecture, specifically to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it seems to be a tumor suppressor.

Gene Information

Human
Gene Name:	FBLN1
Uniprot:	P23142
Entrez:	2192

Family

Belongs to:

fibulin family

Alternative Names

FBLN; FBLN1; FIBL1; FIBL-1; Fibulin 1; fibulin-1

Molecular Weight

Mass (kDA):
77.214 kDA

Genomic Context


Human

Location:	22q13.31
Sequence:	22; NC_000022.11 (45502883..45601135)

Tissue Specificity

Isoform A and isoform B are only expressed in placenta. Isoform C and isoform D are expressed in a variety of tissues and cultured cells.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix.

Diseases

Malignant Neoplasms
Tissue Adhesions
Neoplasms
Carcinoma
Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Syndactyly
Neoplasm Metastasis
Sheep Diseases
Mammary Neoplasms
Retinal Diseases

Dystrophy
Haploinsufficiency
Primary Neoplasm
Crest Syndrome
Stomach Neoplasms
Skin Diseases, Bacterial

Interacting Proteins

LCE5A

Pathways

Cell Adhesion
Localization
Methylation
Cell Cycle
Cell Differentiation
Dna Methylation
Cell Migration
Stem Cell Differentiation
Osteoblast Differentiation
Dna Hypomethylation
Protein Targeting
Protein Catabolic Process
Proteolysis

Immune Response
Mesenchymal Cell Migration
Cell Division
Reverse Transcription
Innate Immune Response
Catabolic Process
Induction Of Apoptosis

PTMs

Methylation

Demethylation

Cleavage

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FBLN1

References

PMID: 2269669 by Argraves W.S., et al. Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure.

PMID: 9106159 by Tran H., et al. Human fibulin-1D: molecular cloning, expression and similarity with S1-5 protein, a new member of the fibulin gene family.