Protocadherin Fat 1 Antibodies

AND FAT1 ELISA kits, Protocadherin Fat 1 Proteins

Many biological assays use antibodies to detect Protocadherin Fat 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protocadherin Fat 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protocadherin Fat 1 antibodies...

We validate the specificity of these antibodies to Protocadherin Fat 1 by testing them on tissues known to express FAT1 positively and negatively. Browse below to find the FAT1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FAT1 Infographic by Boster Bio

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Anti-Protocadherin Fat 1 FAT1 Antibody

Human

IHC

$380
Cat # A01536-1
100ul

FAT1 Overview

Facts about Protocadherin Fat 1.

Protocadherin Fat 1 (FAT1)

Plays an important role for cellular polarization, directed cell migration and regulating cell-cell contact. .

Gene Information

Human
Gene Name:	FAT1
Uniprot:	Q14517
Entrez:	2195

Family

Belongs to:

No superfamily

Alternative Names

FAT tumor suppressor 1; FAT tumor suppressor homolog 1 (Drosophila)

Molecular Weight

Mass (kDA):
506.273 kDA

Genomic Context


Human

Location:	4q35.2
Sequence:	4; NC_000004.12 (186587789..186726696, complement)

Tissue Specificity

Expressed in many epithelial and some endothelial and smooth muscle cells.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Nucleus. Cytoplasm, perinuclear region.

Diseases

Neoplasms
Tissue Adhesions
Malignant Neoplasms
Carcinoma
Cell Invasion
Malignant Neoplasm Of Breast
Neoplasm Invasiveness
Nervousness
Kidney Diseases
Malignant Neoplasm Of Mouth
Colorectal Cancer
Malignant Neoplasm Of Pancreas
Bipolar Disorder

Obesity
Adrenoleukodystrophy
Mammary Neoplasms
Cell Transformation, Neoplastic
Malignant Squamous Cell Neoplasm
Melanoma
Tumor Angiogenesis

Interacting Proteins

ENAH
HOMER3
Homer3

Pathways

Localization
Transport
Cell Growth
Fatty Acid Transport
Cell Adhesion
Cell-cell Adhesion
Cell Proliferation
Cell Migration
Cytokinesis
Pathogenesis
Glomerular Filtration
Cell Death
Cell Division

Cell Motility
Interphase
Cell Morphogenesis
Secretory Pathway
Cell Cycle
Wound Healing
Long-chain Fatty Acid Transport

PTMs

Phosphorylation
Cleavage
Oxidation
Methylation

Acylation
Hydroxylation
Glycosylation
Acetylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FAT1

References

PMID: 8586420 by Dunne J., et al. Molecular cloning and tissue expression of FAT, the human homologue of the Drosophila fat gene that is located on chromosome 4q34-q35 and encodes a putative adhesion molecule.

PMID: 15922730 by Magg T., et al. Processing of the human protocadherin Fat1 and translocation of its cytoplasmic domain to the nucleus.