FANCM Antibodies

AND FANCM ELISA kits, FANCM Proteins

Many biological assays use antibodies to detect FANCM, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FANCM in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FANCM antibodies...

We validate the specificity of these antibodies to FANCM by testing them on tissues known to express FANCM positively and negatively. Browse below to find the FANCM antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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FANCM Infographic by Boster Bio

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Anti-Fanconi anemia group M protein FANCM Antibody

Human

IF, ICC, WB

$405
Cat # A03931
100ul

FANCM Overview

Facts about Fanconi anemia group M protein.

FANCM 3D structure. Source: alphafold

Fanconi anemia group M protein (FANCM)

DNA-dependent ATPase part of the Fanconi anemia (FA) core complex (PubMed:16116422). Required for the normal activation of the FA pathway, resulting in monoubiquitination of the FANCI-FANCD2 complicated in response to DNA damage, cellular resistance to DNA cross-linking medications, and prevention of chromosomal breakage (PubMed:16116422, PubMed:19423727, PubMed:20347428, PubMed:20347429).

In complicated with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates (PubMed:20347428, PubMed:20347429). Its ATP-dependent DNA branch migration activity can process branched DNA structures like a movable replication fork.

Gene Information

Human
Gene Name:	FANCM
Uniprot:	Q8IYD8
Entrez:	57697

Family

Belongs to:

DEAD box helicase family

Alternative Names

ATP-dependent RNA helicase FANCM; EC 3.6.1; FAAP250EC 3.6.4.13; Fanconi anemia, complementation group M; Fanconi anemia-associated polypeptide of 250 kDa; KIAA1596Fanconi anemia group M protein; MGC176453; Protein FACM; Protein Hef ortholog