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FANCG Antibodies
AND FANCG ELISA kits, FANCG Proteins
Many biological assays use antibodies to detect FANCG, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with FANCG in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop FANCG antibodies...
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FANCG Infographic by Boster Bio
All FANCG Products
Product
Figures
Specificity
Applications
Price
Human, Mouse
ELISA, IHC, WB
$629
Cat # A03129
100ug
Cat # A03129
100ug
FANCG Overview
Facts about Fanconi anemia group G protein.
Fanconi anemia group G protein (FANCG)
DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link fix and in the maintenance of normal chromosome stability.
Candidate tumor suppressor gene. .
Gene Information
| Human | |
|---|---|
| Gene Name: | FANCG |
| Uniprot: | O15287 |
| Entrez: | 2189 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
DNA repair protein XRCC9; FAG; Fanconi anemia group G protein; Fanconi anemia, complementation group G; Protein FACG; X-ray repair, complementing defective, in Chinese hamster, 9; XRCC9X-ray repair complementing defective repair in Chinese hamster cells 9
Molecular Weight
Mass (kDA):
68.554 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 9p13.3 |
| Sequence: | 9; NC_000009.12 (35073839..35079942, complement) |
Tissue Specificity
Highly expressed in testis and thymus. Found in lymphoblasts.
Subcellular Localizations
Nucleus. Cytoplasm. The major form is nuclear. The minor form is cytoplasmic.
Diseases
- Anemia
- Fanconi Anemia
- Malignant Neoplasms
- Pancytopenia
- Congenital Abnormality
- Neoplasms
- Hereditary Diseases
- Leukemia
- Chromosome Breakage
- Aplastic Anemia
- Malignant Neoplasm Of Breast
- Carcinoma
- Cytogenetic Abnormality
Interacting Proteins
- FANCA
- FANCF
- SPTAN1
Pathways
- Hypersensitivity
- Dna Repair
- Localization
- Cell Cycle
- Dna Replication
- Translesion Synthesis
- Chromosome Breakage
- Pathogenesis
- Transport
- Mitosis
- Methylation
- Cell Death
- S Phase
PTMs
- Phosphorylation
- Methylation
- Ubiquitination
- Cleavage
Research Areas
- Breast Cancer
- Cancer
- DNA Repair
- Genes Sensitive to DNA Damaging Agents
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/FANCG
bosterbio.com/bosterbio-gene-info-cards/FANCG
References
PMID: 9256465 by Liu N., et al. The human XRCC9 gene corrects chromosomal instability and mutagen sensitivities in CHO UV40 cells.
PMID: 9806548 by De Winter J.P., et al. The Fanconi anaemia group G gene FANCG is identical with XRCC9.