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- Table of Contents
Facts about Myelin-associated neurite-outgrowth inhibitor.
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Human | |
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Gene Name: | FAM168B |
Uniprot: | A1KXE4 |
Entrez: | 130074 |
Belongs to: |
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FAM168 family |
family with sequence similarity 168, member B
Mass (kDA):
20.324 kDA
Human | |
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Location: | 2q21.1 |
Sequence: | 2; NC_000002.12 (131047876..131093468, complement) |
Expressed in the brain, within neuronal axonal fibers and associated with myelin sheets (at protein level). Expression tends to be lower in the brain of Alzheimer disease patients compared to healthy individuals (at protein level).
Cytoplasm, perinuclear region. Cell membrane; Multi-pass membrane protein. Cell projection, axon. Expressed in neuronal cell bodies and axonal fibers.
PMID: 20716133 by Mishra M., et al. The novel protein MANI modulates neurogenesis and neurite-cone growth.
PMID: 22771904 by Mishra M., et al. Characterizing the neurite outgrowth inhibitory effect of Mani.