F2R Antibodies

AND F2R ELISA kits, F2R Proteins

Many biological assays use antibodies to detect F2R, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with F2R in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop F2R antibodies...

We validate the specificity of these antibodies to F2R by testing them on tissues known to express F2R positively and negatively. Browse below to find the F2R antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

Previous: CCN2 Next: F2RL2

F2R Infographic by Boster Bio

All F2R Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Thrombin Receptor/F2R Antibody Picoband®

7 Q&As

Human

IHC, WB

$370
Cat # RP1092
100 μg/vial

Anti-PAR1/Thrombin Receptor/F2r Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A03352-2
100 μg/vial

Anti-PAR1/Thrombin Receptor/F2R Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A03352-1
100 μg/vial

Anti-Thrombin R (S42) F2R Antibody

Human, Mouse, Rat

$405
Cat # A03352S42
100ul

Thrombin Receptor (F2R) (NM_001992) Human Over-expression Lysate

Human

$628
Cat # LS002149
100 µg

F2R Overview

Facts about Proteinase-activated receptor 1.

F2R 3D structure. Source: alphafold

Proteinase-activated receptor 1 (F2R)

High affinity receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation and in cerebral growth.

Gene Information

Human
Gene Name:	F2R
Uniprot:	P25116
Entrez:	2149

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

Cf2r; CF2RHTR; coagulation factor II (thrombin) receptor; Coagulation factor II receptor; F2R; HTR; PAR1; PAR1PAR-1protease-activated receptor 1; Protease-Activated Receptor 1; Thrombin receptor; ThrR; TRGPC; TRproteinase-activated receptor 1

Molecular Weight

Mass (kDA):
47.441 kDA

Genomic Context


Human

Location:	5q13.3
Sequence:	5; NC_000005.10 (76716126..76735770)

Tissue Specificity

Platelets and vascular endothelial cells.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Neoplasm Metastasis
Tumor Angiogenesis
Inflammation
Infarction
Myocardial Infarction
Tissue Adhesions
Rabies (disorder)
Stomach Neoplasms
Carcinoma
Globus Hystericus
Premature Obstetric Labor

Carcinogenesis
Malignant Neoplasm Of Stomach
Thrombosis
Tuberculosis
Adenoma
Coronary Heart Disease
Thromboembolism Of Vein

Interacting Proteins

CAV1
PROCR

Pathways

Coagulation
Angiogenesis
Transport
Blood Coagulation
Immune Response
Hemostasis
Cell Adhesion
Response To Wounding
Cell Migration
Response To Hypoxia
Glycosylation
Localization
Defense Response

Methylation
Reverse Transcription
Cell Motility
Fibrinolysis
Cell Differentiation
Innate Immune Response
Pathogenesis

PTMs

Phosphorylation
Glycosylation

Cleavage
Methylation

Research Areas

Apoptosis
GPCR

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/F2R

References

PMID: 1672265 by Vu T.-K.H., et al. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation.

PMID: 8955127 by Shapiro M.J., et al. Role of the thrombin receptor's cytoplasmic tail in intracellular trafficking. Distinct determinants for agonist-triggered versus tonic internalization and intracellular localization.