Exostosin-1 Antibodies

AND EXT1 ELISA kits, Exostosin-1 Proteins

Many biological assays use antibodies to detect Exostosin-1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Exostosin-1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Exostosin-1 antibodies...

We validate the specificity of these antibodies to Exostosin-1 by testing them on tissues known to express EXT1 positively and negatively. Browse below to find the EXT1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EXT1 Infographic by Boster Bio

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Anti-Exostosin-1 EXT1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC, ICC

$405
Cat # A02086
100ul

EXT1 Overview

Facts about Exostosin-1.

EXT1 3D structure. Source: alphafold

Exostosin-1 (EXT1)

Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone.

Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

Gene Information

Human
Gene Name:	EXT1
Uniprot:	Q16394
Entrez:	2131

Family

Belongs to:

glycosyltransferase 47 family

Alternative Names

EC 2.4.1.224; EC 2.4.1.225; exostoses (multiple) 1; Exostosin 1; exostosin-1; EXT; EXT1; Glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan4-alpha-N-acetylglucosaminyltransferase; Langer-Giedion syndrome chromosome region; LGCR; LGS; Multiple exostoses protein 1; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase; Putative tumor suppressor protein EXT1; TRPS2; TTV

Molecular Weight

Mass (kDA):
86.255 kDA

Genomic Context


Human

Location:	8q24.11
Sequence:	8; NC_000008.11 (117794490..118111826, complement)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. The EXT1/EXT2 complex is localized in the Golgi apparatus.