Exostosin-2 Antibodies

AND EXT2 ELISA kits, Exostosin-2 Proteins

Many biological assays use antibodies to detect Exostosin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Exostosin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Exostosin-2 antibodies...

We validate the specificity of these antibodies to Exostosin-2 by testing them on tissues known to express EXT2 positively and negatively. Browse below to find the EXT2 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EXT2 Infographic by Boster Bio

All EXT2 Products

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Anti-Exostosin-2 EXT2 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A02065
100ul

Anti-EXT2 Antibody (Center)

Human

Flow Cytometry, IF, IHC-P, WB

$299
Cat # A02065-1
80 µl

EXT2 Overview

Facts about Exostosin-2.

EXT2 3D structure. Source: alphafold

Exostosin-2 (EXT2)

Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone.

Appears to be a tumor suppressor. Required for the exosomal release of SDCBP, CD63 and syndecan (PubMed:22660413).

Gene Information

Human
Gene Name:	EXT2
Uniprot:	Q93063
Entrez:	2132

Family

Belongs to:

glycosyltransferase 47 family

Alternative Names

EC 2.4.1.224; EC 2.4.1.225; exostoses (multiple) 2; Exostosin 2; exostosin-2; EXT2; Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan4-alpha-N-acetylglucosaminyltransferase; Multiple Exostoses Protein 2; N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase; Putative tumor suppressor protein EXT2; SOTV

Molecular Weight

Mass (kDA):
82.255 kDA

Genomic Context


Human

Location:	11p11.2
Sequence:	11; NC_000011.10 (44095659..44251981)

Tissue Specificity

Ubiquitous.

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein. The EXT1/EXT2 complex is localized in the Golgi apparatus.