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- Table of Contents
Facts about Ectonucleoside triphosphate diphosphohydrolase 1.
Hydrolyzes ATP and ADP equally well. .
Human | |
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Gene Name: | ENTPD1 |
Uniprot: | P49961 |
Entrez: | 953 |
Belongs to: |
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GDA1/CD39 NTPase family |
ADPase; ATPDase; ATP-diphosphatase; CD39 antigen; CD39; CD39EC 3.6.1.5; DKFZp686D194; DKFZp686I093; EC 3.6.1; ecto-apyrase; Ecto-ATP diphosphohydrolase 1; Ecto-ATPase 1; Ecto-ATPDase 1; ectonucleoside triphosphate diphosphohydrolase 1; ENTPD1; FLJ40921; FLJ40959; Lymphoid cell activation antigen; NTPD1; NTPDase 1; NTPDase-1
Mass (kDA):
57.965 kDA
Human | |
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Location: | 10q24.1 |
Sequence: | 10; NC_000010.11 (95710901..95877266) |
Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. Isoform 1 and isoform 3 are present in both placenta and umbilical vein, whereas isoform 2 is present in placenta only.
Membrane; Multi-pass membrane protein.
PMID: 7930580 by Maliszewski C.R., et al. The CD39 lymphoid cell activation antigen. Molecular cloning and structural characterization.
PMID: 8996251 by Robson S.C., et al. Loss of ATP diphosphohydrolase activity with endothelial cell activation.