ENTPD6 Antibodies

AND ENTPD6 ELISA kits, ENTPD6 Proteins

Many biological assays use antibodies to detect ENTPD6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ENTPD6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ENTPD6 antibodies...

We validate the specificity of these antibodies to ENTPD6 by testing them on tissues known to express ENTPD6 positively and negatively. Browse below to find the ENTPD6 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ENTPD6 Infographic by Boster Bio

All ENTPD6 Products

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Product

Figures

Specificity

Applications

Price

Anti-ENTPD6 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A12017
100ul

Human CD39L2/ENTPD6 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTO75354
Starting from 20ug

ENTPD6 (NM_001247) Human Over-expression Lysate

Human

$628
Cat # LS000955
100 µg

ENTPD6 Overview

Facts about Ectonucleoside triphosphate diphosphohydrolase 6.

ENTPD6 3D structure. Source: alphafold

Ectonucleoside triphosphate diphosphohydrolase 6 (ENTPD6)

Might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent, there isn't any hydrolysis of nucleoside 5'-monophosphates.

The order of activity with different substrates is GDP > IDP >> UDP = CDP >> ADP (By similarity). .

Gene Information

Human
Gene Name:	ENTPD6
Uniprot:	O75354
Entrez:	955

Family

Belongs to:

GDA1/CD39 NTPase family

Alternative Names

CD39 antigen-like 2; CD39L2; CD39L2NTPDase-6; CD39-like 2; dJ738P15.3; DKFZp781G2277; DKFZp781K21102; EC 3.6.1.6; ectonucleoside triphosphate diphosphohydrolase 6 (putative function); ectonucleoside triphosphate diphosphohydrolase 6 (putative); ectonucleoside triphosphate diphosphohydrolase 6; ENTPD6; FLJ36711; IL-6SAG; IL6ST2; interleukin 6 signal transducer-2; NTPD3; NTPDase 6

Molecular Weight

Mass (kDA):
53.246 kDA

Genomic Context


Human

Location:	20p11.21
Sequence:	20; NC_000020.11 (25195670..25228075)

Tissue Specificity

Expressed in most tissues, but predominantly in heart.

Subcellular Localizations

Golgi apparatus membrane; Single-pass type II membrane protein. Secreted. But also occurs in a soluble extracellular form.

Diseases

Malignant Neoplasms
Neoplasms
Insulin Resistance
Diabetes Mellitus, Non-insulin-dependent
Testicular Neoplasms
Seminoma
Malignant Neoplasm Of Testis

Atherosclerosis
Diabetes Mellitus

Pathways

Transport
Ion Transport
Catabolic Process

PTMs

Disulfide bond

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ENTPD6

References

PMID: 9676430 by Chadwick B.P., et al. The CD39-like gene family: identification of three new human members (CD39L2, CD39L3, and CD39L4), their murine homologues, and a member of the gene family from Drosophila melanogaster.

PMID: 14529283 by Ivanenkov V.V., et al. Bacterial expression, characterization, and disulfide bond determination of soluble human NTPDase6 (CD39L2) nucleotidase: implications for structure and function.