Elongation of very long chain fatty acids protein 6 (ELOVL6)

Catalyzes the first and rate-limiting response of the four which constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic procedure, allows the addition of two carbons to the chain of long- and quite long-chain fatty acids/VLCFAs per cycle.

Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with greater activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation level.