Endothelin-1 Antibodies

Endothelin-1 (EDN1)

Endothelins are endothelium-derived vasoconstrictor peptides. .

Gene Information

Human
Gene Name:	EDN1
Uniprot:	P05305
Entrez:	1906

Family

Belongs to:
endothelin/sarafotoxin family

Alternative Names

ARCND3; EDN1; endothelin 1; Endothelin-1; ET1; HDLCQ7; PPET1; preproendothelin-1; QME

Molecular Weight

Mass (kDA):
24.425 kDA

Genomic Context

Human
Location:	6p24.1
Sequence:	6; NC_000006.12 (12256463..12297194)

Tissue Specificity

Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.

Subcellular Localizations

Secreted.

Diseases

• Hypertensive Disease
• Crest Syndrome
• Asthma
• Inflammation
• Malignant Neoplasms
• Cleft Palate
• Congenital Abnormality
• Diabetes Mellitus
• Kidney Diseases
• Craniofacial Abnormalities
• Atherosclerosis
• Diabetes Mellitus, Non-insulin-dependent
• Obesity

• Carcinoma
• Cleft Lip
• Tissue Adhesions
• Tumor Angiogenesis
• Cardiovascular Diseases
• Neoplasms
• Dental Plaque

Interacting Proteins

• EDNRA
• EDNRB

Pathways

• Pathogenesis
• Secretion
• Localization
• Cell Proliferation
• Angiogenesis
• Luteolysis
• Pigmentation
• Inflammatory Response
• Vasoconstriction
• Methylation
• Cell Adhesion
• Cellular Localization
• Cartilage Development

• Cell Death
• Lung Development
• Cell Differentiation
• Cartilage Morphogenesis
• Dna Methylation
• Ovulation
• Excretion

PTMs

• Demethylation
• Cleavage

• Methylation
• Phosphorylation

Research Areas

• Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EDN1

Boster Bio - Best Uses Of The EDN1 Marker

Boster Bio is not without its drawbacks. However, there are a lot of techniques you can use to maximize the results of your experiments using Boster Bio. You can identify and eliminate many errors with troubleshooting guides and optimization tips. These guides will help you get the most value from your experiments and ensure they are running smoothly.

Good

The EDN1 marker can be utilized to track a variety of biological experiments. It has many functions, including the control and support of MITF high populations as well as EDN1 expression. This means that EDN1 an important master regulator of phenotype heterogeneity. At present, there are two methods to block EDN1-expressing cells, and also to target the EDN1 gene it self.

Bad

The EDN1 marker is an intriguing gene that allows researchers to differentiate healthy cells from cancerous. However, there are some bad ways to use the EDN1 marker. The following information will help you decide whether or not your cells are healthy. Let's first determine the cell lines that are used as control. The cell lines we identified were mIMCD-3 cell lines and rats the sgk1.

The EDN1-AS strand-specific human primers were created for laying down closer to the 5' end of the gene. Reverse transcriptase was procured from Thermo Fischer following manufacturer's instructions. Oligo-dT primers were used as positive control for mRNA from the polyadenylated tail. The EDN1 gene is approximately 538 kb in length.

Tangled

Finding the EDN1 marker that is tricky is one of the more difficult tasks in bioinformatics research. Boster provides a range of methods and tools that can be used to deliver high-quality results. Boster Bio offers a wide variety of technical resources, including blogs, disease information and digital tools on the web. To ensure the highest quality of results, Boster Bio also provides high-quality buffers for lysis.