Endothelin-2 Antibodies

AND EDN2 ELISA kits, Endothelin-2 Proteins

Many biological assays use antibodies to detect Endothelin-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Endothelin-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Endothelin-2 antibodies...

We validate the specificity of these antibodies to Endothelin-2 by testing them on tissues known to express EDN2 positively and negatively. Browse below to find the EDN2 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EDN2 Infographic by Boster Bio

All EDN2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Endothelin-2 EDN2 Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A05594
100ul

Human EDN2 Recombinant Protein

SDS-PAGE, Denatured

$250
Cat # PROTP20800
Starting from 20ug

Endothelin 2 (EDN2) (NM_001956) Human Over-expression Lysate

Human

$628
Cat # LS001907
100 µg

EDN2 Overview

Facts about Endothelin-2.

EDN2 3D structure. Source: alphafold

Endothelin-2 (EDN2)

Endothelins are endothelium-derived vasoconstrictor peptides. .

Gene Information

Human
Gene Name:	EDN2
Uniprot:	P20800
Entrez:	1907

Family

Belongs to:

endothelin/sarafotoxin family

Alternative Names

EDN2; endothelin 2; Endothelin2; Endothelin-2; ET2; ET-2; PPET2; preproendothelin 2; preproendothelin-2

Molecular Weight

Mass (kDA):
19.96 kDA

Genomic Context


Human

Location:	1p34.2
Sequence:	1; NC_000001.11 (41478775..41484699, complement)

Tissue Specificity

Expressed in lung, but not in placental stem villi vessels or cultured placental villi smooth muscle cells.

Subcellular Localizations

Secreted.

Diseases

Retinal Degeneration
Inflammation
Hypoxia
Carcinoma
Tumor Angiogenesis
Malignant Neoplasms
Neoplasms
Retinal Diseases
Inflammatory Response
Retinitis Pigmentosa
Crest Syndrome
Hypertensive Disease

Leukemia
Janiceps
Pregnancy Complications
Malignant Neoplasm Of Breast
Malignant Tumor Of Colon
Lung Diseases
Neoplasm Invasiveness

Pathways

Ovulation
Cell Proliferation
Cell Death
Cell Migration
Localization
Inflammatory Response
Angiogenesis
Transport
Gene Silencing
Fertilization
Aging

Metaphase
Defense Response
Methylation
Embryo Implantation
Cell Differentiation
Ovarian Follicle Rupture

PTMs

Methylation

Demethylation

Phosphorylation

Research Areas

Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EDN2

References

PMID: 1701397 by Ohkubo S., et al. Specific expression of human endothelin-2 (ET-2) gene in a renal adenocarcinoma cell line. Molecular cloning of cDNA encoding the precursor of ET-2 and its characterization.

PMID: 1840558 by Bloch K.D., et al. cDNA cloning and chromosomal assignment of the endothelin 2 gene: vasoactive intestinal contractor peptide is rat endothelin 2.