EDC3 Antibodies

AND EDC3 ELISA kits, EDC3 Proteins

Many biological assays use antibodies to detect EDC3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EDC3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EDC3 antibodies...

We validate the specificity of these antibodies to EDC3 by testing them on tissues known to express EDC3 positively and negatively. Browse below to find the EDC3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EDC3 Infographic by Boster Bio

All EDC3 Products

Product

Figures

Specificity

Applications

Price

Anti-EDC3 Antibody

Human, Mouse, Rat

$405
Cat # A04929
100ul

EDC3 (NM_001142443) Human Recombinant Protein

$1249
Cat # PROTQ96F86
20 µg

Anti-Fruit fly Edc3 Antibody

Fruit fly

$470
Cat # DZ41387
200 μl/vial

EDC3 Overview

Facts about Enhancer of mRNA-decapping protein 3.

EDC3 3D structure. Source: alphafold

Enhancer of mRNA-decapping protein 3 (EDC3)

Binds single-stranded RNA.
Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping.

May play a role in spermiogenesis and oogenesis. .

Gene Information

Human
Gene Name:	EDC3
Uniprot:	Q96F86
Entrez:	80153

Family

Belongs to:

EDC3 family

Alternative Names

enhancer of mRNA decapping 3 homolog (S. cerevisiae); enhancer of mRNA-decapping protein 3; FLJ21128; FLJ31777; hYjeF_N2; hYjeF_N2-15q23; LSM16 homolog (EDC3, S. cerevisiae); LSM16 homolog; LSM16; YJDC; yjeF domain containing; YjeF domain-containing protein 1; YjeF N-terminal domain-containing protein 2; yjeF_N2; YJEFN2yjeF domain containing (E.coli)

Molecular Weight

Mass (kDA):
56.078 kDA

Genomic Context


Human

Location:	15q24.1
Sequence:	15; NC_000015.10 (74630558..74696434, complement)

Tissue Specificity

Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland.

Subcellular Localizations

Cytoplasm, P-body. Processing bodies (PB).

Diseases

Physiological Stress
Testicular Neoplasms
Fibroma
Leydig Cell Tumor
Neoplasms

Interacting Proteins

ANXA10
DCP1A
DCP1B
DDX6
EFHC2

ZFP36

Pathways

Translation
Mrna Processing
Nuclear Export
Localization
Termination Of Rna Polymerase Ii Transcription
Transport
Gene Silencing
Filamentous Growth
Stress Granule Assembly

Rna Interference
Oogenesis
Spermatogenesis

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EDC3

References

PMID: 16364915 by Fenger-Groen M., et al. Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.

PMID: 17533573 by Rudolph C., et al. ApoA-I-binding protein (AI-BP) and its homologues hYjeF_N2 and hYjeF_N3 comprise the YjeF_N domain protein family in humans with a role in spermiogenesis and oogenesis.