Protein EVI2B Antibodies

AND EVI2B ELISA kits, Protein EVI2B Proteins

Many biological assays use antibodies to detect Protein EVI2B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein EVI2B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein EVI2B antibodies...

We validate the specificity of these antibodies to Protein EVI2B by testing them on tissues known to express EVI2B positively and negatively. Browse below to find the EVI2B antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EVI2B Infographic by Boster Bio

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EVI2B (NM_006495) Human Over-expression Lysate

Human

$628
Cat # LS002124
100 µg

EVI2B Overview

Facts about Protein EVI2B.

EVI2B 3D structure. Source: alphafold

Protein EVI2B (EVI2B)

Required for granulocyte differentiation and functionality of hematopoietic progenitor cells through the control of cell cycle progression and survival of hematopoietic progenitor cells. .

Gene Information

Human
Gene Name:	EVI2B
Uniprot:	P34910
Entrez:	2124

Family

Belongs to:

No superfamily

Alternative Names

CD361 antigen; D17S376; Ecotropic viral integration site 2B protein homolog; ecotropic viral integration site 2B; EVDBprotein EVI2B; EVI-2B

Molecular Weight

Mass (kDA):
48.666 kDA

Genomic Context


Human

Location:	17q11.2
Sequence:	17; NC_000017.11 (31303770..31314149, complement)

Tissue Specificity

Bone marrow, peripheral blood mononuclear cells, fibroblasts and Epstein-Barr virus-transformed lymphoblastoid cell lines. Strongly expressed in granulocytic cells, and weakly on lymphocytes cells.

Subcellular Localizations

Membrane; Single-pass type I membrane protein.

Diseases

Neurofibromatosis 1
Neurofibromatoses
Neoplasms
Neurofibroma
Malignant Neoplasms
Leukemia
Fracture Of First Cervical Vertebra
Microphthalmos
Melanoma
Chromosome Break
Learning Disabilities

Carcinogenesis
Chromosome Breakage
Malignant Neoplasm Of Ovary
Colorectal Cancer
Chronic Lymphocytic Leukemia
Rectal Carcinoma

Pathways

Methylation
Glycosylation
Dna Methylation
Pigmentation
Metaphase
Leukocyte Differentiation
Keratinocyte Differentiation

Pathogenesis
Cell-cell Adhesion

PTMs

Glycoprotein

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EVI2B

References

PMID: 1903357 by Cawthon R.M., et al. cDNA sequence and genomic structure of EVI2B, a gene lying within an intron of the neurofibromatosis type 1 gene.

PMID: 28186500 by Zjablovskaja P., et al. EVI2B is a C/EBPalpha target gene required for granulocytic differentiation and functionality of hematopoietic progenitors.