Envoplakin Antibodies

AND EVPL ELISA kits, Envoplakin Proteins

Many biological assays use antibodies to detect Envoplakin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Envoplakin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Envoplakin antibodies...

We validate the specificity of these antibodies to Envoplakin by testing them on tissues known to express EVPL positively and negatively. Browse below to find the EVPL antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EVPL Infographic by Boster Bio

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Anti-Envoplakin EVPL Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A09421
100ul

EVPL Overview

Facts about Envoplakin.

EVPL 3D structure. Source: alphafold

Envoplakin (EVPL)

Component of the cornified envelope of keratinocytes. May connect the cornified envelope to desmosomes and intermediate filaments.

Gene Information

Human
Gene Name:	EVPL
Uniprot:	Q92817
Entrez:	2125

Family

Belongs to:

plakin or cytolinker family

Alternative Names

210 KDa Cornified Envelope Precursor Protein; 210 KDa Paraneoplastic Pemphigus Antigen; envoplakin; EVPK; p210

Molecular Weight

Mass (kDA):
231.604 kDA

Genomic Context


Human

Location:	17q25.1
Sequence:	17; NC_000017.11 (76006845..76027306, complement)

Tissue Specificity

Exclusively expressed in stratified squamous epithelia.

Subcellular Localizations

Cell junction, desmosome. Cornified envelope. Cytoplasm, cytoskeleton. Colocalized with DSP at desmosomes and along intermediate filaments.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Esophagus
Keratoderma, Palmoplantar, Diffuse
Carcinoma
Esophageal Neoplasms
Malignant Squamous Cell Neoplasm
Palmoplantar Keratosis
Adenocarcinoma
Squamous Cell Carcinoma Of Esophagus
Neoplasms
Barrett's Adenocarcinoma
Bullous Pemphigoid

Keratosis
Hereditary Diseases
Melanoma
Laryngeal Neoplasm
Hereditary Malignant Neoplasm
Dental Plaque

Pathways

Cell Communication
Localization

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EVPL

References

PMID: 8707850 by Ruhrberg C., et al. Envoplakin, a novel precursor of the cornified envelope that has homology to desmoplakin.

PMID: 10409435 by Risk J.M., et al. Envoplakin, a possible candidate gene for focal NEPPK/esophageal cancer (TOC): the integration of genetic and physical maps of the TOC region on 17q25.