ETFB Antibodies

AND ETFB ELISA kits, ETFB Proteins

Many biological assays use antibodies to detect ETFB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ETFB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ETFB antibodies...

We validate the specificity of these antibodies to ETFB by testing them on tissues known to express ETFB positively and negatively. Browse below to find the ETFB antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ETFB Infographic by Boster Bio

All ETFB Products

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Product

Figures

Specificity

Applications

Price

Anti-ETFB Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A05431
100ul

ETFB (NM_001985) Human Recombinant Protein

$813
Cat # PROTP38117
20 µg

ETFB (NM_001985) Human Over-expression Lysate

Human

$628
Cat # LS002109
100 µg

ETFB Overview

Facts about Electron transfer flavoprotein subunit beta.

ETFB 3D structure. Source: alphafold

Electron transfer flavoprotein subunit beta (ETFB)

Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase (PubMed:25416781, PubMed:15159392, PubMed:15975918). It transfers the electrons to the key mitochondrial respiratory chain through ETF-ubiquinone oxidoreductase (Probable).

Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism (PubMed:12815589, PubMed:7912128). ETFB binds an AMP molecule that likely has a purely structural role (PubMed:8962055, PubMed:15159392, PubMed:15975918).

Gene Information

Human
Gene Name:	ETFB
Uniprot:	P38117
Entrez:	2109

Family

Belongs to:

ETF beta-subunit/FixA family

Alternative Names

beta-ETF; electron transfer flavoprotein beta subunit; electron transfer flavoprotein beta-subunit; electron transfer flavoprotein subunit beta; electron transfer flavoprotein, beta polypeptide; electron-transfer-flavoprotein, beta polypeptide; electron-transferring-flavoprotein, beta polypeptide; MADD

Molecular Weight

Mass (kDA):
27.844 kDA

Genomic Context


Human

Location:	19q13.41
Sequence:	19; NC_000019.10 (51345155..51366388, complement)

Tissue Specificity

Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas.

Subcellular Localizations

Mitochondrion matrix.

Diseases

Multiple Acyl Coenzyme A Dehydrogenase Deficiency
Myopathy
Metabolic Diseases
Inborn Errors Of Metabolism
Mitochondrial Diseases
Hypoglycemia
Acidemia
Lipid Metabolism Disorders
Mutation, Out-of-frame
Weakness

Endoplasmic Reticulum Stress
Insulin Resistance
Fibrosis
Renal Carnitine Transport Defect

Interacting Proteins

ETFA
ETFRF1

Pathways

Transport
Electron Transport
Lipid Storage
Nadh Oxidation
Insulin Secretion
Fatty Acid Beta-oxidation
Riboflavin Transport
Localization
Senescence
Protein Destabilization
Fermentation

Translation
Tissue Remodeling
Fibroblast Activation
Pathogenesis
Glycolysis
Secretion

PTMs

Oxidation

Reduction

Research Areas

Lipid and Metabolism

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ETFB

References

PMID: 8504797 by Finocchiaro G., et al. cDNA cloning and mitochondrial import of the beta-subunit of the human electron-transfer flavoprotein.

PMID: 12815589 by Olsen R.K.J., et al. Clear relationship between ETF/ETFDH genotype and phenotype in patients with multiple acyl-CoA dehydrogenation deficiency.