ETAA1 Antibodies

AND ETAA1 ELISA kits, ETAA1 Proteins

Many biological assays use antibodies to detect ETAA1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ETAA1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ETAA1 antibodies...

We validate the specificity of these antibodies to ETAA1 by testing them on tissues known to express ETAA1 positively and negatively. Browse below to find the ETAA1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ETAA1 Infographic by Boster Bio

All ETAA1 Products

Product

Figures

Specificity

Applications

Price

Anti-ETAA1 Antibody

Human, Rat

$405
Cat # A14604
100ul

ETAA1 (NM_019002) Human Over-expression Lysate

Human

$628
Cat # LS054465
100 µg

ETAA1 Overview

Facts about Ewing's tumor-associated antigen 1.

ETAA1 3D structure. Source: alphafold

Ewing's tumor-associated antigen 1 (ETAA1)

Replication stress response protein that accumulates at DNA damage sites and promotes replication fork progression and integrity (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with the RPA complex and directly stimulates ATR kinase activity independently of TOPBP1 (PubMed:27723720, PubMed:27723717).

Likely only regulates a subset of ATR targets (PubMed:27723720, PubMed:27723717). .

Gene Information

Human
Gene Name:	ETAA1
Uniprot:	Q9NY74
Entrez:	54465

Family

Belongs to:

No superfamily

Alternative Names

ETAA16; Ewing tumor-associated antigen 1; ewing's tumor-associated antigen 1; FLJ22647

Molecular Weight

Mass (kDA):
103.44 kDA

Genomic Context


Human

Location:	2p14
Sequence:	2; NC_000002.12 (67397317..67412089)

Tissue Specificity

Expressed at high levels in the brain, liver kidney and Ewing tumor cell lines.

Subcellular Localizations

Nucleus. Localizes at sites of DNA damage following replication stress (PubMed:27601467, PubMed:27723720, PubMed:27723717). Recruited to stalled replication forks via interaction with RPA1 and RPA2 subunits of the RPA complex (PubMed:27601467, PubMed:27723720).

Diseases

Neoplasms
Dental Plaque
Bone Neoplasms
Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)

PTMs

Isopeptide bond

Phosphoprotein

Ubl conjugation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ETAA1

References

PMID: 16003559 by Borowski A., et al. Structure and function of ETAA16: a novel cell surface antigen in Ewing's tumours.

PMID: 27601467 by Feng S., et al. Ewing Tumor-associated Antigen 1 interacts with replication protein A to promote restart of stalled replication forks.