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- Table of Contents
Facts about ERO1-like protein beta.
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Human | |
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Gene Name: | ERO1B |
Uniprot: | Q86YB8 |
Entrez: | 56605 |
Belongs to: |
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EROs family |
DKFZp779C1042; DKFZp779I0141; EC 1.8.4; EC 1.8.4.-; Endoplasmic oxidoreductin-1-like protein B; ERO1-L(beta); ERO1-L-beta; ERO1-like beta (S. cerevisiae); ERO1-like protein beta; FLJ11003; oxidoreductin-1-L-beta
Mass (kDA):
53.543 kDA
Human | |
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Location: | 1q42.3 |
Sequence: | 1; NC_000001.11 (236213064..236281983, complement) |
Highly expressed in the digestive tract, including the duodenum and lower digestive tract. In the stomach, highly expressed in enzyme-producing chief cells (at protein level). In the pancreas, expressed in islets of Langerhans and, at lower levels, in enzyme-secreting cells (at protein level). Detected at low level in many other tissues.
Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. The association with ERP44 may be essential for its retention in the endoplasmic reticulum.
PMID: 10818100 by Pagani M., et al. Endoplasmic reticulum oxidoreductin 1-lbeta (ERO1-Lbeta), a human gene induced in the course of the unfolded protein response.
PMID: 11707400 by Mezghrani A., et al. Manipulation of oxidative protein folding and PDI redox state in mammalian cells.