EPS8L2 Antibodies

AND EPS8L2 ELISA kits, EPS8L2 Proteins

Many biological assays use antibodies to detect EPS8L2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EPS8L2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EPS8L2 antibodies...

We validate the specificity of these antibodies to EPS8L2 by testing them on tissues known to express EPS8L2 positively and negatively. Browse below to find the EPS8L2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EPS8L2 Infographic by Boster Bio

All EPS8L2 Products

Product

Figures

Specificity

Applications

Price

Anti-Eps8L2 Antibody

5 Q&As

Human, Mouse

$399
Cat # A11064
100μl

Anti-EPS8L2 (K30) Antibody

Human, Mouse, Rat

$405
Cat # A11064-1
100ul

Anti-Eps8L2 Antibody

Human, Mouse

ELISA, IF, IHC, WB

$380
Cat # A11064-2
100ul

EPS8L2 (NM_022772) Human Over-expression Lysate

Human

$628
Cat # LS064787
100 µg

EPS8L2 Overview

Facts about Epidermal growth factor receptor kinase substrate 8-like protein 2.

EPS8L2 3D structure. Source: alphafold

Epidermal growth factor receptor kinase substrate 8-like protein 2 (EPS8L2)

Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton.

In the cochlea, is needed for stereocilia maintenance in mature hair cells (By similarity). .

Gene Information

Human
Gene Name:	EPS8L2
Uniprot:	Q9H6S3
Entrez:	64787

Family

Belongs to:

EPS8 family

Alternative Names

epidermal growth factor receptor kinase substrate 8-like protein 2; Epidermal growth factor receptor pathway substrate 8-related protein 2; EPS8-like 2; EPS8-like protein 2; EPS8R2; EPS8-related protein 2; FLJ16738; FLJ21935; FLJ22171; MGC126530; MGC3088

Molecular Weight

Mass (kDA):
80.621 kDA

Genomic Context


Human

Location:	11p15.5
Sequence:	11; NC_000011.10 (706202..727727)

Tissue Specificity

Detected in fibroblasts and placenta.

Subcellular Localizations

Cytoplasm. Cell projection, stereocilium. Localizes at the tips of the stereocilia of the inner and outer hair cells.

Diseases

Carcinoma
Malignant Neoplasms
Neoplasms
Testicular Neoplasms
Hypothyroidism
Malignant Germ Cell Tumor
Embryonal Carcinoma
Endometrial Neoplasms
Endometrial Polyp

Neoplasms, Germ Cell And Embryonal
Hyperthyroidism
Endometrial Carcinoma
Germ Cell Tumor

Pathways

Transport
Cell Activation
T Cell Activation
Hypersensitivity

PTMs

Phosphorylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EPS8L2

References

PMID: 12620401 by Tocchetti A., et al. In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure.

PMID: 14565974 by Offenhaeuser N., et al. The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway.