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- Table of Contents
Facts about Ectopic P granules protein 5 homolog.
Involved in autophagy.
May play a role in a late step of autophagy, such as clearance of autophagosomal cargo..
Human | |
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Gene Name: | EPG5 |
Uniprot: | Q9HCE0 |
Entrez: | 57724 |
Belongs to: |
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EPG5 family |
DKFZp667P2311; ectopic P granules protein 5 homolog; ectopic P-granules autophagy protein 5 homolog (C. elegans); HEEW1; hEPG5; KIAA1632
Mass (kDA):
292.481 kDA
Human | |
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Location: | 18q12.3-q21.1 |
Sequence: | 18; NC_000018.10 (45800586..45967339, complement) |
Cytoplasm, perinuclear region. Lysosome.
PMID: 20550938 by Tian Y., et al. C. elegans screen identifies autophagy genes specific to multicellular organisms.
PMID: 29130391 by Piano Mortari E., et al. The Vici syndrome protein EPG5 regulates intracellular nucleic acid trafficking linking autophagy to innate and adaptive immunity.