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- Table of Contents
Facts about BRCA2-interacting transcriptional repressor EMSY.
As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. .
Human | |
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Gene Name: | EMSY |
Uniprot: | Q7Z589 |
Entrez: | 56946 |
Belongs to: |
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No superfamily |
BRCA2-interacting transcriptional repressor EMSY
Mass (kDA):
141.468 kDA
Human | |
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Location: | 11q13.5 |
Sequence: | 11; NC_000011.10 (76444928..76553031) |
Nucleus. Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process.
PMID: 14651845 by Hughes-Davies L., et al. EMSY links the BRCA2 pathway to sporadic breast and ovarian cancer.
PMID: 19131338 by Garapaty S., et al. Identification and characterization of a novel nuclear protein complex involved in nuclear hormone receptor-mediated gene regulation.