Elastin Antibodies

AND ELN ELISA kits, Elastin Proteins

Many biological assays use antibodies to detect Elastin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Elastin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Elastin antibodies...

We validate the specificity of these antibodies to Elastin by testing them on tissues known to express ELN positively and negatively. Browse below to find the ELN antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ELN Infographic by Boster Bio

All ELN Products

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Anti-Elastin ELN Antibody (Monoclonal, BA-4)

1 Citations 3 Q&As

Bovine, Human

IHC

$370
Cat # MA1038
100 μg/vial

Anti-Elastin ELN Antibody

Human, Mouse, Rat

$405
Cat # A01300
100ul

ELN Overview

Facts about Elastin.

ELN 3D structure. Source: alphafold

Elastin (ELN)

Major structural protein of tissues such as aorta and nuchal ligament, which must expand quickly and recover completely. Molecular determinant of the late vascular morphogenesis, stabilizing arterial structure by regulating proliferation and organization of vascular smooth muscle (By similarity).

Gene Information

Human
Gene Name:	ELN
Uniprot:	P15502
Entrez:	2006

Family

Belongs to:

elastin family

Alternative Names

elastin; FLJ38671; FLJ43523; SVAS; tropoelastin; WBS; WS

Molecular Weight

Mass (kDA):
68.398 kDA

Genomic Context


Human

Location:	7q11.23
Sequence:	7; NC_000007.14 (74027772..74069907)

Tissue Specificity

Expressed within the outer myometrial smooth muscle and throughout the arteriolar tree of uterus (at protein level). Also expressed in the large arteries, lung and skin.

Subcellular Localizations

Secreted, extracellular space, extracellular matrix. Extracellular matrix of elastic fibers.

Diseases

Williams Syndrome
Stenosis
Aortic Valve Stenosis
Supravalvular Aortic Stenosis
Haploinsufficiency
Leukemia
Aneurysm
Hypertensive Disease
Myeloid Leukemia
Myeloid Leukemia, Chronic
Vascular Diseases
Intracranial Aneurysm

Cutis Laxa
Neoplasms
Developmental Disabilities
Hypercalcemia
Malignant Neoplasms
Leukemia, Myelocytic, Acute
Aortic Aneurysm

Interacting Proteins

EFEMP2
FBLN5
LOX

Pathways

Pathogenesis
Aging
Cognition
Cell Proliferation
Lung Development
Localization
Translation
Cell Cycle
Metaphase
Regeneration
Social Behavior
Transport
Cell Activation

Muscle Cell Proliferation
Proteolysis
Dosage Compensation
Reflex
Inflammatory Response
Mrna Stabilization
Vasoconstriction

PTMs

Phosphorylation

Biotinylation

Research Areas

Extracellular Matrix

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ELN

References

PMID: 3039501 by Indik Z., et al. Alternative splicing of human elastin mRNA indicated by sequence analysis of cloned genomic and complementary DNA.

PMID: 3171221 by Fazio M.J., et al. Cloning of full-length elastin cDNAs from a human skin fibroblast recombinant cDNA library: further elucidation of alternative splicing utilizing exon-specific oligonucleotides.

1 Publications of Boster Elastin Antibodies & ELISA Kits

PubMed ID: 32344246, Mega Putra IG,Ngurah Warsita IG,Suwiyoga K,Fajar Manuaba IBG,Budiana ING,Putra W...

*More publications can be found for each product on its corresponding product page