ELAC1 Antibodies

AND ELAC1 ELISA kits, ELAC1 Proteins

Many biological assays use antibodies to detect ELAC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ELAC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ELAC1 antibodies...

We validate the specificity of these antibodies to ELAC1 by testing them on tissues known to express ELAC1 positively and negatively. Browse below to find the ELAC1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ELAC1 Infographic by Boster Bio

All ELAC1 Products

Product

Figures

Specificity

Applications

Price

ELAC1 (NM_018696) Human Recombinant Protein

$1249
Cat # PROTQ9H777
20 µg

ELAC1 (NM_018696) Human Over-expression Lysate

Human

$628
Cat # LS055520
100 µg

ELAC1 Overview

Facts about Zinc phosphodiesterase ELAC protein 1.

ELAC1 3D structure. Source: alphafold

Zinc phosphodiesterase ELAC protein 1 (ELAC1)

Zinc phosphodiesterase, which shows some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

Gene Information

Human
Gene Name:	ELAC1
Uniprot:	Q9H777
Entrez:	55520

Family

Belongs to:

RNase Z family

Alternative Names

D29elaC (E. coli) homolog 1; Deleted in Ma29; EC 3.1.26.11; elaC homolog 1 (E. coli); ElaC homolog protein 1; FLJ59261; Ribonuclease Z 1; RNase Z 1; tRNA 3 endonuclease 1; tRNA 3' processing endoribonuclease; tRNA Z (short form); tRNase Z 1; tRNase ZS; zinc phosphodiesterase ELAC protein 1

Molecular Weight

Mass (kDA):
40.019 kDA

Genomic Context


Human

Location:	18q21.2
Sequence:	18; NC_000018.10 (50968040..50988121)

Tissue Specificity

Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Subcellular Localizations

Cytoplasm, cytosol. Nucleus. Mainly cytosolic.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Prostate
Lung Neoplasms
Prostatic Neoplasms
Neoplasms
Salivary Gland Diseases
Malignant Neoplasm Of Lung

Growth Arrest
Carcinogenesis

Pathways

Trna Processing
Dna Replication
Cell Proliferation
Translation
Cell Growth
Trna 3'-end Processing
Rna Interference

Localization

PTMs

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ELAC1

References

PMID: 11401430 by Yanaihara N., et al. Physical and transcriptional map of a 311-kb segment of chromosome 18q21, a candidate lung tumor suppressor locus.

PMID: 11175785 by Tavtigian S.V., et al. A candidate prostate cancer susceptibility gene at chromosome 17p.