EIF2B5 Antibodies

AND EIF2B5 ELISA kits, EIF2B5 Proteins

Many biological assays use antibodies to detect EIF2B5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF2B5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF2B5 antibodies...

We validate the specificity of these antibodies to EIF2B5 by testing them on tissues known to express EIF2B5 positively and negatively. Browse below to find the EIF2B5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EIF2B5 Infographic by Boster Bio

All EIF2B5 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-EIF2B5 Antibody

Human, Mouse, Rat

IP, IF, IHC, ICC, WB

$405
Cat # A03801
100ul

Anti-eIF2B epsilon Rabbit Monoclonal Antibody

Human

IF, IHC, ICC, WB

$370
Cat # M03801
100 μl/vial

eIF2B epsilon (EIF2B5) (NM_003907) Human Over-expression Lysate

Human

$628
Cat # LS008893
100 µg

EIF2B5 Overview

Facts about Translation initiation factor eIF-2B subunit epsilon.

EIF2B5 3D structure. Source: alphafold

Translation initiation factor eIF-2B subunit epsilon (EIF2B5)

Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. .

Gene Information

Human
Gene Name:	EIF2B5
Uniprot:	Q13144
Entrez:	8893

Family

Belongs to:

eIF-2B gamma/epsilon subunits family

Alternative Names

CACH; CLE; eIF-2B GDP-GTP exchange factor subunit epsilon; EIF-2B; EIF2BE; EIF2Bepsilon; eukaryotic translation initiation factor 2B, subunit 5 (epsilon, 82kD); eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa; LVWM; translation initiation factor eIF-2B subunit epsilon

Molecular Weight

Mass (kDA):
80.38 kDA

Genomic Context


Human

Location:	3q27.1
Sequence:	3; NC_000003.12 (184135023..184145311)

Diseases

Leukoencephalopathies
Ataxia
Brain Diseases
Leukoencephalopathy With Vanishing White Matter
Leukodystrophy
Demyelinating Diseases
Craniocerebral Trauma
Nervousness
Atrophy
Premature Menopause

Muscle Spasticity
Demyelination
Cystic Degeneration
Sclerosis
Cach/vwm Syndrome

Interacting Proteins

GSK3B

Pathways

Translation
Cellular Senescence
Fertilization
Axon Regeneration
Glycosylation
Localization
Myelination
Inflammatory Response
Senescence
Regeneration
Cell Cycle

Cell Death
Protein Folding
Angiogenesis
Regulation Of Translation
Rna Interference

PTMs

Acetylation

Methylation

Research Areas

DNA Repair
DNA replication, Transcription, Translation and Splicing

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EIF2B5

References

PMID: 8688466 by Asuru A.I., et al. Cloning and characterization of cDNAs encoding the epsilon-subunit of eukaryotic initiation factor-2B from rabbit and human.

PMID: 8397507 by Welsh G.I., et al. Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B.