EIF2A Antibodies

AND EIF2A ELISA kits, EIF2A Proteins

Many biological assays use antibodies to detect EIF2A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EIF2A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EIF2A antibodies...

We validate the specificity of these antibodies to EIF2A by testing them on tissues known to express EIF2A positively and negatively. Browse below to find the EIF2A antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EIF2A Infographic by Boster Bio

All EIF2A Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-eIF-2a (Phospho-S51) Antibody

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$405
Cat # A02418S51
100ul

Anti-eIF2A Rabbit Monoclonal Antibody

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M02418
100 μl/vial

EIF2A (NM_032025) Human Over-expression Lysate

Human

$628
Cat # LS083939
100 µg

EIF2A Overview

Facts about Eukaryotic translation initiation factor 2A.

EIF2A 3D structure. Source: alphafold

Eukaryotic translation initiation factor 2A (EIF2A)

Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits.

In contrast to the eIF- 2 complex, it binds methionyl-tRNAi to 40S subunits in a codon- dependent fashion, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. .

Gene Information

Human
Gene Name:	EIF2A
Uniprot:	Q9BY44
Entrez:	83939

Family

Belongs to:

WD repeat EIF2A family

Alternative Names

EIF-2; EIF-2A; EIF2AEIF2; EIF-2alpha; eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa; subunit 1 (alpha, 35kD )

Molecular Weight

Mass (kDA):
64.99 kDA

Genomic Context


Human

Location:	3q25.1
Sequence:	3; NC_000003.12 (150546678..150586016)

Tissue Specificity

Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta.

Diseases

Endoplasmic Reticulum Stress
Malignant Neoplasms
Hepatitis
Hepatitis C
Infective Disorder
Virus Diseases
Inflammatory Bowel Diseases
Paramyotonia Congenita (disorder)
Intestinal Diseases
Ulcer
Injury To Liver
Periodic Paralysis (finding)
Brain Infarction

Osteochondritis Dissecans
Cold Intolerance
Brain Injuries
Ischemia
Arterial Occlusion
Fetal Death
Physiological Stress

Pathways

Translation
Protein Phosphorylation
Cell Cycle
Hyperphosphorylation
Response To Stress
Cell Death
Methanogenesis
Invasive Growth

Localization
Apoptotic Process
Autophagy

PTMs

Phosphorylation

Cleavage

Dephosphorylation

Research Areas

Chromatin Research
DNA Repair
Lipid and Metabolism
Phospho-Specific
Translation Control

Unfolded Protein Response

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EIF2A

References

PMID: 12133843 by Zoll W.L., et al. Characterization of mammalian eIF2A and identification of the yeast homolog.