EGR2 Antibodies

AND EGR2 ELISA kits, EGR2 Proteins

Many biological assays use antibodies to detect EGR2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with EGR2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop EGR2 antibodies...

We validate the specificity of these antibodies to EGR2 by testing them on tissues known to express EGR2 positively and negatively. Browse below to find the EGR2 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EGR2 Infographic by Boster Bio

All EGR2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-EGR2 Antibody Picoband®

16 Q&As

Human, Mouse, Rat

$370
Cat # PA2178
100 μg/vial

Anti-EGR2 Mouse Monoclonal Antibody [Clone ID: OTI1B12]

Human, Mouse, Rat

IF, IHC, WB

$523
Cat # M00921
100 µl

Anti-EGR2 Rabbit Monoclonal Antibody

Human, Mouse, Rat

$370
Cat # M00921-1
100 μl/vial

Anti-EGR2 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, WB

$370
Cat # A00921-1
100 μg/vial

EGR2 Overview

Facts about E3 SUMO-protein ligase EGR2.

EGR2 3D structure. Source: alphafold

E3 SUMO-protein ligase EGR2 (EGR2)

Sequence-specific DNA-binding transcription factor. Binds to two specific DNA sites located in the promoter region of HOXA4.

Gene Information

Human
Gene Name:	EGR2
Uniprot:	P11161
Entrez:	1959

Family

Belongs to:

EGR C2H2-type zinc-finger protein family

Alternative Names

AT591; CMT1D; CMT4E; early growth response 2 (Krox-20 homolog, Drosophila); early growth response 2; early growth response protein 2; EGR-2; FLJ14547; Krox-20 homolog, Drosophila; KROX-20, Drosophila, homolog (early growth response-2); KROX20DKFZp686J1957; Zinc finger protein Krox-20

Molecular Weight

Mass (kDA):
50.302 kDA

Genomic Context


Human

Location:	10q21.3
Sequence:	10; NC_000010.11 (62811996..62819167, complement)

Subcellular Localizations

Nucleus.

Diseases

Charcot-marie-tooth Disease
Nervousness
Peripheral Neuropathy
Neoplasms
Crest Syndrome
Hereditary Motor And Sensory Neuropathies
Malignant Neoplasms
Congenital Hypomyelinating Neuropathy
Demyelinating Diseases
Dejerine-sottas Disease (disorder)
Inherited Neuropathy
Tissue Adhesions

Demyelination
Atrophy
Inflammation
Carcinoma
Autoimmune Reaction
Schizophrenia

Pathways

Myelination
Segmentation
Cell Cycle
Cell Proliferation
Cell Development
Pathogenesis
Hindbrain Development
Schwann Cell Development
Cell Differentiation
Cell Death
Regeneration
Cell Activation
Localization

Nerve Development
Schwann Cell Proliferation
Schwann Cell Differentiation
Secretion
T Cell Anergy
Macrophage Differentiation
Transport

PTMs

Phosphorylation
Methylation
Acetylation
Cleavage

Ubiquitination
Sumoylation
Demethylation
Reduction

Oxidation

Research Areas

Chromatin Research
Neurodegeneration
Neuroscience
Transcription Factors and Regulators
Zinc Finger

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EGR2

References

PMID: 3140236 by Joseph L.J., et al. Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with 'zinc-binding finger' structure.

PMID: 9537424 by Warner L.E., et al. Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies.