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Endothelin-3 Antibodies

AND EDN3 ELISA kits, Endothelin-3 Proteins

Many biological assays use antibodies to detect Endothelin-3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Endothelin-3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Endothelin-3 antibodies...

We validate the specificity of these antibodies to Endothelin-3 by testing them on tissues known to express EDN3 positively and negatively. Browse below to find the EDN3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EDN3 Infographic by Boster Bio

EDN3 protein infographic

All EDN3 Products

Product

Figures

Specificity

Applications

Price

Human Endothelin-3 Recombinant Protein

SDS-PAGE

$350
Cat # PROTP14138
Starting from 10ug

Anti-Endothelin 3 (EDN3) Mouse Monoclonal Antibody [Clone ID: OTI3E10]

Human

IHC

$523
Cat # M03272
100 µl

Endothelin 3 (EDN3) (NM_000114) Human Over-expression Lysate

Human

$628
Cat # LS001908
100 µg

EDN3 Overview

Facts about Endothelin-3.

EDN3 3D structure

EDN3 3D structure. Source: alphafold

Endothelin-3 (EDN3)

Endothelins are endothelium-derived vasoconstrictor peptides. .

Gene Information

Human
Gene Name:	EDN3
Uniprot:	P14138
Entrez:	1908

Gene Information

Family

Belongs to:

endothelin/sarafotoxin family

Family

Alternative Names

EDN3; endothelin 3; Endothelin3; Endothelin-3; ET3; ET-3; HSCR4; MGC15067; MGC61498; PPET3; preproendothelin-3; truncated endothelin 3; WS4B

Molecular Weight

Mass (kDA):
25.454 kDA

Molecular Weight

Genomic Context


Human

Location:	20q13.32
Sequence:	20; NC_000020.11 (59300415..59325992)

Tissue Specificity

Expressed in trophoblasts and placental stem villi vessels, but not in cultured placental smooth muscle cells.

Subcellular Localizations

Secreted.

Subcellular Localization

Diseases

Hirschsprung Disease
Crest Syndrome
Waardenburg Syndrome
Nervousness
Megacolon
Metrorrhagia
Congenital Abnormality
Congenital Disorders
Waardenburg Syndrome, Type 4a
Complete Hearing Loss
Intestinal Obstruction
Neoplasms
Sensorineural Hearing Loss (disorder)

Hypopigmentation Disorder
Malignant Neoplasms
Total Colonic Aganglionosis
Hypoventilation
Constipation
Down Syndrome
Intestinal Diseases

Disease

Pathways

Pigmentation
Pathogenesis
Localization
Cell Proliferation
Melanocyte Differentiation
Cell Migration
Developmental Process
Embryo Implantation
System Development
Cell Differentiation
Neuroblast Migration
Nervous System Development
Cell Growth

Innervation
Gene Silencing
Neural Crest Cell Migration
Immune Response
Neurogenesis
Skin Development
Complement Activation

Pathways

PTMs

Cleavage

Methylation

Demethylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EDN3

References

PMID: 2509452 by Bloch K.D., et al. cDNA cloning and chromosomal assignment of the gene encoding endothelin 3.

PMID: 2178974 by Onda H., et al. One of the endothelin gene family, endothelin 3 gene, is expressed in the placenta.