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- Table of Contents
Facts about Enhancer of mRNA-decapping protein 3.
Binds single-stranded RNA.
Involved in the process of mRNA degradation and in the positive regulation of mRNA decapping.May play a role in spermiogenesis and oogenesis. .
Human | |
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Gene Name: | EDC3 |
Uniprot: | Q96F86 |
Entrez: | 80153 |
Belongs to: |
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EDC3 family |
enhancer of mRNA decapping 3 homolog (S. cerevisiae); enhancer of mRNA-decapping protein 3; FLJ21128; FLJ31777; hYjeF_N2; hYjeF_N2-15q23; LSM16 homolog (EDC3, S. cerevisiae); LSM16 homolog; LSM16; YJDC; yjeF domain containing; YjeF domain-containing protein 1; YjeF N-terminal domain-containing protein 2; yjeF_N2; YJEFN2yjeF domain containing (E.coli)
Mass (kDA):
56.078 kDA
Human | |
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Location: | 15q24.1 |
Sequence: | 15; NC_000015.10 (74630558..74696434, complement) |
Expressed in theca and granulosa cells in ovary, and in spermatids of the meiotic division part II and apical membrane of Sertoli cells in testis (at protein level). Also expressed in brain and mammary gland.
Cytoplasm, P-body. Processing bodies (PB).
PMID: 16364915 by Fenger-Groen M., et al. Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.
PMID: 17533573 by Rudolph C., et al. ApoA-I-binding protein (AI-BP) and its homologues hYjeF_N2 and hYjeF_N3 comprise the YjeF_N domain protein family in humans with a role in spermiogenesis and oogenesis.