Ectodysplasin-A Antibodies

AND EDA ELISA kits, Ectodysplasin-A Proteins

Many biological assays use antibodies to detect Ectodysplasin-A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Ectodysplasin-A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Ectodysplasin-A antibodies...

We validate the specificity of these antibodies to Ectodysplasin-A by testing them on tissues known to express EDA positively and negatively. Browse below to find the EDA antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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EDA Infographic by Boster Bio

All EDA Products

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Product

Figures

Specificity

Applications

Price

Anti-Ectodysplasin-A EDA Antibody Picoband®

2 Citations

Human, Mouse, Rat

$370
Cat # PA1561
100 μg/vial

Anti-EDA Antibody Picoband®

1 Citations 1 Q&As

Human

$370
Cat # PB9191
100 μg/vial

Anti-EDA1 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A01113
0.1 mg

Anti-EDA Antibody (N-term)

Human

Flow Cytometry, IHC-P, WB

$299
Cat # A01113-1
80 µl

EDA Overview

Facts about Ectodysplasin-A.

EDA 3D structure. Source: alphafold

Ectodysplasin-A (EDA)

Cytokine that's involved in epithelial-mesenchymal signaling during morphogenesis of ectodermal organs. Functions as a ligand activating the DEATH-domain containing receptors EDAR and EDA2R (PubMed:8696334, PubMed:11039935, PubMed:27144394).

May also play a role in cell adhesion (By similarity). .

Gene Information

Human
Gene Name:	EDA
Uniprot:	Q92838
Entrez:	1896

Family

Belongs to:

tumor necrosis factor family

Alternative Names

EDAA2; EDA-A2

Molecular Weight

Mass (kDA):
41.294 kDA

Genomic Context


Human

Location:	Xq13.1
Sequence:	X; NC_000023.11 (69616086..70039472)

Tissue Specificity

Not abundant; expressed in specific cell types of ectodermal (but not mesodermal) origin of keratinocytes, hair follicles, sweat glands. Also in adult heart, liver, muscle, pancreas, prostate, fetal liver, uterus, small intestine and umbilical chord.

Subcellular Localizations

Cell membrane; Single-pass type II membrane protein.; [Ectodysplasin-A, secreted form]: Secreted.

Diseases

Ectodermal Dysplasia
Dysplasia
Christ-siemens-touraine Syndrome
Pain
Anhydrotic Ectodermal Dysplasias
Neoplasms
Nervousness
Hypodontia
Depressive Disorder
Malignant Neoplasms
Tissue Adhesions
Hypohidrosis
Developmental Absence Of Tooth

Anxiety Disorders
Cerebrovascular Accident
Pain, Postoperative
Congenital Absence
Carcinoma
Hereditary Diseases
Inflammation

Interacting Proteins

ATP6V0C
CYB561
DOLK
EMP3
GIMAP5

MAL
NIPAL3
OSTC
PLN
SEC22A

Pathways

Pathogenesis
Habituation
Localization
Wound Healing
Secretion
Cell Adhesion
Regeneration
Cell Proliferation
Hair Follicle Development
Gland Development
Conjugation
Entner-doudoroff Pathway
Appendage Development

Transport
Aging
Cell Migration
Methylation
Sweat Gland Development
Cell Differentiation
Cell Growth

PTMs

Phosphorylation
Cleavage
Amidation
Oxidation
Methylation
Amination
Nitration
Reduction
Glycosylation
Carboxylation

Phosphorothioation
Biotinylation
Acetylation
Demethylation
Hydroxylation
Acylation
Ribosylation
Ubiquitination
Iodination
Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/EDA

References

PMID: 8696334 by Kere J., et al. X-linked anhidrotic (hypohidrotic) ectodermal dysplasia is caused by mutation in a novel transmembrane protein.

PMID: 9683615 by Monreal A.W., et al. Identification of a new splice form of the EDA1 gene permits detection of nearly all X-linked hypohidrotic ectodermal dysplasia mutations.

2 Publications of Boster Ectodysplasin-A Antibodies & ELISA Kits

PubMed ID: 10.1016/j.cca.2019.09.009, Circulating ectodysplasin A is a potential biomarker for nonalcoholic fatty live...
PubMed ID: 25206454, X-irradiation for inhibiting glial scar formation in injured spinal cord

*More publications can be found for each product on its corresponding product page