Transcription factor E2F6 Antibodies

AND E2F6 ELISA kits, Transcription factor E2F6 Proteins

Many biological assays use antibodies to detect Transcription factor E2F6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Transcription factor E2F6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Transcription factor E2F6 antibodies...

We validate the specificity of these antibodies to Transcription factor E2F6 by testing them on tissues known to express E2F6 positively and negatively. Browse below to find the E2F6 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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E2F6 Infographic by Boster Bio

All E2F6 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Transcription factor E2F6 E2F6 Antibody Picoband®

4 Q&As

Human, Mouse, Rat

$370
Cat # PA1811
100 μg/vial

Anti-Transcription factor E2F6 E2F6 Antibody

Human, Mouse

ChIP, IP, IF, IHC, WB

$405
Cat # A05062
100ul

Anti-E2F-6 Antibody

Human, Mouse, Rat

ELISA, IHC, WB

$380
Cat # A05062-1
100ul

Anti-E2F6 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IF, ICC, WB

$370
Cat # M05062
100 μl/vial

E2F6 (NM_198256) Human Over-expression Lysate

Human

$628
Cat # LS001876
100 µg

E2F6 Overview

Facts about Transcription factor E2F6.

E2F6 3D structure. Source: alphafold

Transcription factor E2F6 (E2F6)

Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a taste for the 5'-TTTCCCGC-3' E2F recognition website.

E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to control a subset of E2F-dependent genes whose products are necessary for entry into the cell cycle but not for normal cell cycle progression.

Gene Information

Human
Gene Name:	E2F6
Uniprot:	O75461
Entrez:	1876

Family

Belongs to:

E2F/DP family

Alternative Names

E2F transcription factor 6; E2F-6MGC111545; transcription factor E2F6

Molecular Weight

Mass (kDA):
31.844 kDA

Genomic Context


Human

Location:	2p25.1
Sequence:	2; NC_000002.12 (11444375..11466177, complement)

Tissue Specificity

Expressed in all tissues examined. Highest levels in placenta, skeletal muscle, heart, ovary, kidney, small intestine and spleen.

Subcellular Localizations

Nucleus.

Diseases

Neoplasms
Retinoblastoma
Malignant Neoplasms
Carcinoma
Hyperplasia
Mammary Neoplasms
Multiple Acyl Coenzyme A Dehydrogenase Deficiency
Malignant Paraganglionic Neoplasm
Malignant Neoplasm Of Breast
Growth Arrest
Osteosarcoma
Cell Transformation, Neoplastic
Lymphoma

Cancer Of Nasopharynx
Carcinogenesis
Malignant Squamous Cell Neoplasm
Perineurioma
Nasopharyngeal Neoplasms
Nerve Sheath Tumors
Hypoxia

Interacting Proteins

KRTAP10-7
MAX
TFDP1
TFDP2

Pathways

Cell Cycle
Methylation
Cell Proliferation
Gene Silencing
S Phase
Dna Methylation
Cell Cycle Arrest
Cell Growth
Translation
Meiosis
Rna Interference
Regulation Of Cell Cycle
Dna Repair

Dna Replication
Regulation Of Gene Expression
Histone Modification
Oxidative Phosphorylation
Reverse Transcription
Histone Methylation
Chromatin Remodeling

PTMs

Methylation
Reduction
Phosphorylation

Acetylation
Demethylation
Cleavage

Biotinylation

Research Areas

Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/E2F6

References

PMID: 9689056 by Gaubatz S., et al. Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6.

PMID: 9704927 by Cartwright P., et al. E2F-6: a novel member of the E2F family is an inhibitor of E2F- dependent transcription.