DPYSL3 Antibodies

AND DPYSL3 ELISA kits, DPYSL3 Proteins

Many biological assays use antibodies to detect DPYSL3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DPYSL3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DPYSL3 antibodies...

We validate the specificity of these antibodies to DPYSL3 by testing them on tissues known to express DPYSL3 positively and negatively. Browse below to find the DPYSL3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DPYSL3 Infographic by Boster Bio

All DPYSL3 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-CRMP4/Dpysl3 Antibody Picoband®

Rat

$370
Cat # A05960-1
100 μg/vial

Anti-CRMP4 Rabbit Monoclonal Antibody

Human, Mouse, Rat

IP, IF, ICC, WB

$370
Cat # M05960
100 μl/vial

CRMP4 (DPYSL3) (NM_001387) Human Over-expression Lysate

Human

$960
Cat # LS001809
100 µg

DPYSL3 Overview

Facts about Dihydropyrimidinase-related protein 3.

DPYSL3 3D structure. Source: alphafold

Dihydropyrimidinase-related protein 3 (DPYSL3)

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).

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Gene Information

Human
Gene Name:	DPYSL3
Uniprot:	Q14195
Entrez:	1809

Family

Belongs to:

metallo-dependent hydrolases superfamily

Alternative Names

Collapsin response mediator protein 4; CRMP-4; CRMP4collapsin response mediator protein 4 long; dihydropyrimidinase-like 3; DRP-3dihydropyrimidinase-related protein 3; DRP3ULIP1; ULIP-1; ULIPLCRMP; Unc-33-like phosphoprotein 1

Molecular Weight

Mass (kDA):
61.963 kDA

Genomic Context


Human

Location:	5q32
Sequence:	5; NC_000005.10 (147390808..147510068, complement)

Tissue Specificity

Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.

Subcellular Localizations

Cytoplasm. Cell projection, growth cone. Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.

Diseases

Nervousness
Neuroblastoma
Malignant Neoplasms
Tissue Adhesions
Neoplasms
Paroxysmal Nocturnal Dyspnea
Malignant Neoplasm Of Lung
Lung Neoplasms
Glioblastoma
Retinoblastoma
Neoplasm Metastasis
Non-neoplastic Disorder
Metastatic Malignant Neoplasm To The Lymph Node

Thymus Neoplasms
Thymoma
Down Syndrome
Anaplastic Astrocytoma
Hypoxia
Myopathy
Dysplasia

Interacting Proteins

ACD
CRMP1
DPYSL2

Pathways

Cell Adhesion
Neurogenesis
Regeneration
Axon Guidance
Hyperphosphorylation
Mitosis
Brain Development
Immune Response
Neural Rod Formation
Localization
Methylation

Cytoskeleton Organization
Schwann Cell Differentiation
System Development
Cell Death
Nervous System Development
Cell Differentiation

PTMs

Phosphorylation

Cleavage

Methylation

Research Areas

Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DPYSL3

References

PMID: 8973361 by Hamajima N., et al. A novel gene family defined by human dihydropyrimidinase and three related proteins with differential tissue distribution.

PMID: 9115293 by Gaetano C., et al. Identification and characterization of a retinoic acid-regulated human homologue of the unc-33-like phosphoprotein gene (hUlip) from neuroblastoma cells.