DPYSL3 Antibodies

Dihydropyrimidinase-related protein 3 (DPYSL3)

Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration (By similarity).

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Gene Information

Human
Gene Name:	DPYSL3
Uniprot:	Q14195
Entrez:	1809

Family

Belongs to:
metallo-dependent hydrolases superfamily

Alternative Names

Collapsin response mediator protein 4; CRMP-4; CRMP4collapsin response mediator protein 4 long; dihydropyrimidinase-like 3; DRP-3dihydropyrimidinase-related protein 3; DRP3ULIP1; ULIP-1; ULIPLCRMP; Unc-33-like phosphoprotein 1

Molecular Weight

Mass (kDA):
61.963 kDA

Genomic Context

Human
Location:	5q32
Sequence:	5; NC_000005.10 (147390808..147510068, complement)

Tissue Specificity

Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.

Subcellular Localizations

Cytoplasm. Cell projection, growth cone. Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone.

Diseases

• Nervousness
• Neuroblastoma
• Malignant Neoplasms
• Tissue Adhesions
• Neoplasms
• Paroxysmal Nocturnal Dyspnea
• Malignant Neoplasm Of Lung
• Lung Neoplasms
• Glioblastoma
• Retinoblastoma
• Neoplasm Metastasis
• Non-neoplastic Disorder
• Metastatic Malignant Neoplasm To The Lymph Node

• Thymus Neoplasms
• Thymoma
• Down Syndrome
• Anaplastic Astrocytoma
• Hypoxia
• Myopathy
• Dysplasia

Interacting Proteins

• ACD
• CRMP1
• DPYSL2

Pathways

• Cell Adhesion
• Neurogenesis
• Regeneration
• Axon Guidance
• Hyperphosphorylation
• Mitosis
• Brain Development
• Immune Response
• Neural Rod Formation
• Localization
• Methylation

• Cytoskeleton Organization
• Schwann Cell Differentiation
• System Development
• Cell Death
• Nervous System Development
• Cell Differentiation

PTMs

• Phosphorylation

• Cleavage

• Methylation

Research Areas

• Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DPYSL3

Best Uses Of The DPYSL3 Marker

The DPYSL3 marker is an essential part of biomarker experiments, but what exactly are the best uses of this marker? The Boster Bio guide offers several tips to optimize your experiment. There are many flow options. Check out the guide to determine which one is the best. Boster offers high quality primary antibodies with optimized flow methods. Continue reading for optimization tips & guides.

Boster offers primary antibodies with high affinity

Using DPYSL3 to measure protein expression is a simple and reliable way to do so. Boster offers a range antibodies against this marker that react with Rat proteins. The antibodies are not hazardous and can be ordered without BSA. They are also available with blocking protein, which is priced according the immunogen length.