Chloride anion exchanger Antibodies

AND SLC26A3 ELISA kits, Chloride anion exchanger Proteins

Many biological assays use antibodies to detect Chloride anion exchanger, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Chloride anion exchanger in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Chloride anion exchanger antibodies...

We validate the specificity of these antibodies to Chloride anion exchanger by testing them on tissues known to express SLC26A3 positively and negatively. Browse below to find the SLC26A3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC26A3 Infographic by Boster Bio

All SLC26A3 Products

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Anti-DRA SLC26A3 Antibody

6 Q&As

Human, Mouse, Rat

ELISA, WB

$399
Cat # A03335
100 μl

SLC26A3 (NM_000111) Human Over-expression Lysate

Human

$628
Cat # LS001811
100 µg

SLC26A3 Overview

Facts about Chloride anion exchanger.

SLC26A3 3D structure. Source: alphafold

Chloride anion exchanger (SLC26A3)

Chloride/bicarbonate exchanger. Mediates the efficient absorption of chloride ions in the colon, participating in fluid homeostasis.

Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation. .

Gene Information

Human
Gene Name:	SLC26A3
Uniprot:	P40879
Entrez:	1811

Family

Belongs to:

SLC26A/SulP transporter (TC 2.A.53) family

Alternative Names

chloride anion exchanger; CLD; congenital chloride diarrhea; down-regulated in adenoma protein; DRADown-regulated in adenoma; Protein DRA; Solute carrier family 26 member 3; solute carrier family 26, member 3

Molecular Weight

Mass (kDA):
84.505 kDA

Genomic Context


Human

Location:	7q22.3-q31.1
Sequence:	7; NC_000007.14 (107765469..107803223, complement)

Subcellular Localizations

Apical cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Localized in sperm membranes. Midpiece of sperm tail. Colocalizes with CFTR at the midpiece of sperm tail (By similarity).

Diseases

Diarrhea
Adenoma
Cystic Fibrosis
Fibrosis
Congenital Secretory Diarrhea, Chloride Type
Lymphoproliferative Disorder Of The Skin
Dehydration
Colonic Neoplasms
Malignant Neoplasms
Adenocarcinoma
Colitis
Alkalosis
Inflammation

Metabolic Alkalosis
Inborn Errors Of Metabolism
Neoplasms
Inflammatory Bowel Diseases
Ulcer
Malignant Tumor Of Colon
Polyhydramnios

Interacting Proteins

SLC9A3R2

Pathways

Transport
Secretion
Pathogenesis
Localization
Ion Transport
Anion Transport
Sulfate Transport
Bicarbonate Transport
Chloride Transport
Excretion
Cell Adhesion
Proteolysis
Membrane Depolarization

Cell Cycle
Cell Proliferation
Glycosylation
Sperm Capacitation
Clathrin-mediated Endocytosis
Electron Transport
Electron Transport Chain

PTMs

Phosphorylation
Biotinylation
Glycosylation

Sulphation
Nitration
Oxidation

Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC26A3

References

PMID: 7683425 by Schweinfest C.W., et al. Identification of a colon mucosa gene that is down-regulated in colon adenomas and adenocarcinomas.

PMID: 8140616 by Sandal N.N., et al. Similarities between a soybean nodulin, Neurospora crassa sulphate permease II and a putative human tumour suppressor.