Docking protein 5 Antibodies

AND DOK5 ELISA kits, Docking protein 5 Proteins

Many biological assays use antibodies to detect Docking protein 5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Docking protein 5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Docking protein 5 antibodies...

We validate the specificity of these antibodies to Docking protein 5 by testing them on tissues known to express DOK5 positively and negatively. Browse below to find the DOK5 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DOK5 Infographic by Boster Bio

All DOK5 Products

Product

Figures

Specificity

Applications

Price

Anti-Docking protein 5 DOK5 Antibody

Mouse, Rat

$405
Cat # A11431
100ul

Anti-Dok-5 Antibody

Human, Mouse

ELISA, WB

$380
Cat # A11431-1
100ul

DOK5 (NM_018431) Human Over-expression Lysate

Human

$628
Cat # LS055816
100 µg

DOK5 Overview

Facts about Docking protein 5.

DOK5 3D structure. Source: alphafold

Docking protein 5 (DOK5)

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes.

DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.

Gene Information

Human
Gene Name:	DOK5
Uniprot:	Q9P104
Entrez:	55816

Family

Belongs to:

DOK family

Alternative Names

C20orf180; chromosome 20 open reading frame 180; dJ805C22.1; docking protein 5; Downstream of tyrosine kinase 5; Insulin receptor substrate 6; IRS6; IRS-6; MGC16926

Molecular Weight

Mass (kDA):
35.464 kDA

Genomic Context


Human

Location:	20q13.2
Sequence:	20; NC_000020.11 (54475593..54651171)

Tissue Specificity

Highest expression in skeletal muscle, lower in brain, heart and kidney. Also detected in activated peripheral blood T-lymphocytes.

Diseases

Neoplasms
Malignant Neoplasms
Malignant Paraganglionic Neoplasm
Diabetes Mellitus
Diabetes Mellitus, Non-insulin-dependent
Cholangiocarcinoma
Endocrine Gland Neoplasms
Neoplasm Metastasis
Disease Of Adrenal Medulla
Melanoma
Tumor Progression
Hypoxia
Malignant Neoplasm Of Lung

Nervousness
Pheochromocytoma
Osteolysis
Cytogenetic Abnormality
Bipolar Disorder
Cell Invasion
Adenocarcinoma

Pathways

Methylation
Cell Adhesion
Cell Growth
Localization
Rna Interference
Chromatin Remodeling

PTMs

Phosphorylation

Methylation

Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DOK5

References

PMID: 12595900 by Favre C., et al. DOK4 and DOK5: new Dok-related genes expressed in human T cells.

PMID: 12730241 by Cai D., et al. Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5.