DNAJA3 Antibodies

AND DNAJA3 ELISA kits, DNAJA3 Proteins

Many biological assays use antibodies to detect DNAJA3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DNAJA3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DNAJA3 antibodies...

We validate the specificity of these antibodies to DNAJA3 by testing them on tissues known to express DNAJA3 positively and negatively. Browse below to find the DNAJA3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DNAJA3 Infographic by Boster Bio

All DNAJA3 Products

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Product

Figures

Specificity

Applications

Price

Anti-DNAJA3 Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A05761
100ul

TID1 (DNAJA3) (NM_005147) Human Over-expression Lysate

Human

$628
Cat # LS009093
100 µg

DNAJA3 Overview

Facts about DnaJ homolog subfamily A member 3, mitochondrial.

DNAJA3 3D structure. Source: alphafold

DnaJ homolog subfamily A member 3, mitochondrial (DNAJA3)

Modulates apoptotic signal transduction or effector structures inside the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation.

Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging representative mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma- mediated transcriptional activity.

Gene Information

Human
Gene Name:	DNAJA3
Uniprot:	Q96EY1
Entrez:	9093

Family

Belongs to:

No superfamily

Alternative Names

DnaJ (Hsp40) homolog, subfamily A, member 3; DnaJ protein Tid-1; HCA57; Hepatocellular carcinoma-associated antigen 57; hTid-1FLJ45758; TID1dnaJ homolog subfamily A member 3, mitochondrial; tumorous imaginal discs homolog; Tumorous imaginal discs protein Tid56 homolog

Molecular Weight

Mass (kDA):
52.489 kDA

Genomic Context


Human

Location:	16p13.3
Sequence:	16; NC_000016.10 (4425805..4456775)

Tissue Specificity

Widely expressed with highest levels in heart, liver, lung and skeletal muscles. Also expressed in keratinocytes.

Subcellular Localizations

Mitochondrion matrix. Cytoplasm, cytosol. Cell junction, synapse, postsynaptic cell membrane; Peripheral membrane protein. Recruited to the postsynaptic cell membrane of the neuromuscular junction through interaction with MUSK.

Diseases

Neoplasms
Malignant Neoplasms
Cell Transformation, Neoplastic
Carcinoma
Mammary Neoplasms
Malignant Neoplasm Of Breast
Hypoxia
Malignant Paraganglionic Neoplasm
Adenomatous Polyposis Coli
Polyposis
Colorectal Cancer
Cell Invasion

Malignant Squamous Cell Neoplasm
Neoplasm Metastasis
Malnutrition
Melanoma
Neoplasms, Experimental
Malignant Tumor Of Colon
Myasthenic Syndromes, Congenital

Interacting Proteins

C2CD6
CARM1
FAM214B
FOSL2
FRMD6

GCC1
INPP5J
KDM1A
MET
NOC4L

OSGIN1
PRMT6
Ptch1
STAT5B
Stat5b

STK16

Pathways

Cell Death
Cell Proliferation
Localization
Cell Growth
Rna Interference
Cell Migration
Mitochondrial Translocation
Induction Of Apoptosis
Protein Folding
Secretion
Programmed Cell Death
Cellular Senescence
Aging

Inflammatory Response
Cytoskeleton Organization
Mrna Splicing
Cell Motility
Cell Differentiation
Protein Import
Actin Cytoskeleton Organization

PTMs

Phosphorylation

Cleavage

Ubiquitination

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DNAJA3

References

PMID: 9683573 by Schilling B., et al. A novel human DnaJ protein, hTid-1, a homolog of the Drosophila tumor suppressor protein Tid56, can interact with the human papillomavirus type 16 E7 oncoprotein.

PMID: 11679576 by Sarkar S., et al. hTid-1, a human DnaJ protein, modulates the interferon signaling pathway.