Protein unc-119 homolog A Antibodies

AND UNC119 ELISA kits, Protein unc-119 homolog A Proteins

Many biological assays use antibodies to detect Protein unc-119 homolog A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Protein unc-119 homolog A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Protein unc-119 homolog A antibodies...

We validate the specificity of these antibodies to Protein unc-119 homolog A by testing them on tissues known to express UNC119 positively and negatively. Browse below to find the UNC119 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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UNC119 Infographic by Boster Bio

All UNC119 Products

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Retinal protein 4 (UNC119) (NM_005148) Human Recombinant Protein

$813
Cat # PROTQ13432
20 µg

Retinal protein 4 (UNC119) (NM_005148) Human Over-expression Lysate

Human

$628
Cat # LS009094
100 µg

UNC119 Overview

Facts about Protein unc-119 homolog A.

UNC119 3D structure. Source: alphafold

Protein unc-119 homolog A (UNC119)

Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid- binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization.

Binds myristoylated GNAT1 and is needed for G-protein localization and trafficking in sensory neurons. Probably plays a role in trafficking proteins in photoreceptor cells.

Gene Information

Human
Gene Name:	UNC119
Uniprot:	Q13432
Entrez:	9094

Family

Belongs to:

PDE6D/unc-119 family

Alternative Names

hRG4; HRG4POC7 centriolar protein homolog A; POC7; POC7A; protein unc-119 homolog A; Retinal protein 4; RG4; unc119 (C.elegans) homolog; unc-119 homolog (C. elegans)

Molecular Weight

Mass (kDA):
26.962 kDA

Genomic Context


Human

Location:	17q11.2
Sequence:	17; NC_000017.11 (28546707..28552633, complement)

Tissue Specificity

Abundantly expressed in retina, in photoreceptor synapses and inner segments. Expressed in a much lesser extent in several other tissues.

Subcellular Localizations

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, spindle. Localizes to the centrosome in interphase cells and begins to translocate from the spindle pole to the spindle midzone after the onset of mitosis; it then localizes to the intercellular bridge in telophase cells and to the midbody in cytokinetic cells.