Acyl-CoA-binding protein Antibodies

AND DBI ELISA kits, Acyl-CoA-binding protein Proteins

Many biological assays use antibodies to detect Acyl-CoA-binding protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Acyl-CoA-binding protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Acyl-CoA-binding protein antibodies...

We validate the specificity of these antibodies to Acyl-CoA-binding protein by testing them on tissues known to express DBI positively and negatively. Browse below to find the DBI antibody that suites your experiment. We have 7 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DBI Infographic by Boster Bio

All DBI Products

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Specificity

Applications

Price

Anti-Diazepam Binding Inhibitor/DBI Antibody Picoband®

1 Q&As

Human

Flow Cytometry, IF, IHC, IHC-F, ICC, WB

$370
Cat # A01267
100 μg/vial

Anti-ACBP DBI Antibody

3 Q&As

Human, Mouse, Rat

$399
Cat # A01267-1
100μl

Anti-ACBP DBI Antibody

Human

ELISA, IHC, WB

$380
Cat # A01267-2
100ul

Mouse Acbp Recombinant Protein

SDS-PAGE

$250
Cat # PROTP31786
Starting from 20ug

Diazepam Binding Inhibitor (DBI) (NM_020548) Human Recombinant Protein

$1062
Cat # PROTP07108
20 µg

Anti-Diazepam Binding Inhibitor (DBI) Mouse Monoclonal Antibody [Clone ID: OTI4A8]

Human

$523
Cat # M01267
100 µl

Diazepam Binding Inhibitor (DBI) (NM_020548) Human Over-expression Lysate

Human

$628
Cat # LS001622
100 µg

DBI Overview

Facts about Acyl-CoA-binding protein.

DBI 3D structure. Source: alphafold

Acyl-CoA-binding protein (DBI)

Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor.

It is thus possible that this protein also acts as a neuropeptide to modulate the activity of the GABA receptor. .

Gene Information

Human
Gene Name:	DBI
Uniprot:	P07108
Entrez:	1622

Family

Belongs to:

ACBP family

Alternative Names

acyl-Coenzyme A binding domain containing 1; acyl-Coenzyme A bindingprotein); CCK-RP; cholecystokinin-releasing peptide, trypsin-sensitive; diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein); Diazepam-binding inhibitor; endozepine; EP; GABA receptor modulator; MGC70414

Molecular Weight

Mass (kDA):
10.044 kDA

Genomic Context


Human

Location:	2q14.2
Sequence:	2; NC_000002.12 (119366977..119372560)

Tissue Specificity

Isoform 1 is ubiquitous, with a moderate expression level. Isoform 2 is ubiquitous with high level in liver and adipose tissue. Isoform 3 is ubiquitous with strong expression in adipose tissue and heart.

Subcellular Localizations

Endoplasmic reticulum. Golgi apparatus. Golgi localization is dependent on ligand binding (PubMed:17953517).

Diseases

Diabetes Mellitus
Anxiety Disorders
Nervousness
Neoplasms
Substance Withdrawal Syndrome
Ischemia
Pituitary Diseases
Depressive Disorder
Malignant Neoplasms
Brain Injuries
Stress, Psychological
Alzheimer's Disease

Hepatic Encephalopathy
Diffuse Brain Injury
Physiological Stress
Pain
Encephalopathies
Steal Syndrome

Pathways

Secretion
Transport
Localization
Insulin Secretion
Cell Proliferation
Pathogenesis
Cholesterol Transport
Cell Growth
Excretion
Aging
Cell Death
Transposition
Glial Cell Proliferation

Cold Acclimation
Regulation Of Cholesterol Transport
Cellular Localization
Drinking Behavior
Immune Response
Reverse Transcription
Phagocytosis

PTMs

Cleavage
Phosphorylation
Phosphorothioation
Reduction

Nitration
Oxidation
Methylation
Acylation

Research Areas

Cancer

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DBI

References

PMID: 3020548 by Gray P.W., et al. Cloning and expression of cDNA for human diazepam binding inhibitor, a natural ligand of an allosteric regulatory site of the gamma- aminobutyric acid type A receptor.

PMID: 2881742 by Webb N.R., et al. Bovine and human cDNA sequences encoding a putative benzodiazepine receptor ligand.