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- Table of Contents
Facts about Dual specificity protein phosphatase 23.
Able to increase activation of JNK and p38 (MAPK14). .
Human | |
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Gene Name: | DUSP23 |
Uniprot: | Q9BVJ7 |
Entrez: | 54935 |
Belongs to: |
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protein-tyrosine phosphatase family |
dual specificity phosphatase 23; dual specificity protein phosphatase 23; DUSP25; EC 3.1.3.16; EC 3.1.3.48; FLJ20442; LDP3; LDP-3; Low molecular mass dual specificity phosphatase 3; low-molecular-mass dual-specificity phosphatase 3; MOSP; RP11-190A12.1; VH1-like member Z; VH1-like phosphatase Z; VHZ
Mass (kDA):
16.588 kDA
Human | |
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Location: | 1q23.2 |
Sequence: | 1; NC_000001.11 (159780962..159782543) |
Widely expressed. Highly expressed in spleen, prostate, colon, adrenal gland, mammary gland, thyroid and trachea. Expressed at lower level in uterus, small intestine, bladder, bone marrow, brain, spinal cord and stomach.
Cytoplasm, cytosol. Nucleus. Mainly cytosolic. Also nuclear.
PMID: 15281913 by Takagaki K., et al. Characterization of a novel low-molecular-mass dual-specificity phosphatase-3 (LDP-3) that enhances activation of JNK and p38.
PMID: 15201283 by Alonso A., et al. The minimal essential core of a cysteine-based protein-tyrosine phosphatase revealed by a novel 16-kDa VH1-like phosphatase, VHZ.