DUSP22 Antibodies

AND DUSP22 ELISA kits, DUSP22 Proteins

Many biological assays use antibodies to detect DUSP22, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with DUSP22 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop DUSP22 antibodies...

We validate the specificity of these antibodies to DUSP22 by testing them on tissues known to express DUSP22 positively and negatively. Browse below to find the DUSP22 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DUSP22 Infographic by Boster Bio

All DUSP22 Products

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Product

Figures

Specificity

Applications

Price

Anti-DUSP22 Antibody

7 Q&As

Human, Mouse

$360
Cat # A06503
100 µl

Human DuSP22 Recombinant Protein

SDS-PAGE, Denatured

$265
Cat # PROTQ9NRW4
Starting from 20ug

DUSP22 (NM_020185) Human Over-expression Lysate

Human

$628
Cat # LS056940
100 µg

DUSP22 Overview

Facts about Dual specificity protein phosphatase 22.

DUSP22 3D structure. Source: alphafold

Dual specificity protein phosphatase 22 (DUSP22)

Activates the Jnk signaling pathway. Dephosphorylates and deactivates p38 and stress-activated protein kinase/c-Jun N- terminal kinase (SAPK/JNK) (By similarity).

Gene Information

Human
Gene Name:	DUSP22
Uniprot:	Q9NRW4
Entrez:	56940

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

dual specificity phosphatase 22; dual specificity protein phosphatase 22; EC 3.1.3.16; EC 3.1.3.48; FLJ35864; homolog of mouse dual specificity phosphatase LMW-DSP2; JKAP; JNK-stimulating phosphatase 1; JSP-1; JSP1JNK-stimulatory phosphatase-1; LMWDSP2; LMW-DSP2; Low molecular weight dual specificity phosphatase 2; Mitogen-activated protein kinase phosphatase x; MKP-x; MKPXMAP kinase phosphatase x; VHX

Molecular Weight

Mass (kDA):
20.91 kDA

Genomic Context


Human

Location:	6p25.3
Sequence:	6; NC_000006.12 (292057..351355)

Tissue Specificity

Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.

Subcellular Localizations

Cytoplasm. Nucleus.

Diseases

Malignant Neoplasms
Malignant Neoplasm Of Breast
Neoplasms
Mammary Neoplasms
Lymphoma
T-cell Lymphoma
Vaccinia
Peripheral T-cell Lymphoma
Leukemia
Neoplasm Metastasis
Malignant Neoplasm Of Lung
Carcinogenesis

Carcinoma
Dysplasia
Scoliosis, Unspecified
Chromosome Breakage
Dwarfism
Steroid Sulfatase Deficiency Disease
Chronic Lymphocytic Leukemia

Pathways

Protein Phosphorylation
Cell Activation
Cell Migration
T Cell Activation
Dna Repair
Localization
Methylation
Cell Division
Cell Motility
Cell Cycle

Ubiquitin Cycle
Pachytene
Embryonic Morphogenesis
Rna Interference

PTMs

Dephosphorylation
Phosphorylation

Myristoylation
Methylation

Research Areas

GPCR
MAP Kinase Signaling
Protein Phosphatase

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DUSP22

References

PMID: 11717427 by Shen Y., et al. Activation of the Jnk signaling pathway by a dual-specificity phosphatase, JSP-1.

PMID: 20553486 by Schwertassek U., et al. Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis.