Desmoglein-2 Antibodies

AND DSG2 ELISA kits, Desmoglein-2 Proteins

Many biological assays use antibodies to detect Desmoglein-2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Desmoglein-2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Desmoglein-2 antibodies...

We validate the specificity of these antibodies to Desmoglein-2 by testing them on tissues known to express DSG2 positively and negatively. Browse below to find the DSG2 antibody that suites your experiment. We have 8 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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DSG2 Infographic by Boster Bio

All DSG2 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Desmoglein 2/DSG2 Antibody Picoband®

1 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # PA1559
100 μg/vial

Anti-Desmoglein 2 Monoclonal Antibody

7 Q&As

Human, Mouse, Rat

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M02035
100 μl

Anti-Desmoglein 2/DSG2 Antibody Picoband®

Human

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A02035
100 μg/vial

Anti-Dsg2 (V440) Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A02035-1
100ul

Anti-Desmoglein 2 DSG2 Antibody

Human, Mouse, Rat

Flow Cytometry, IHC, WB

$405
Cat # A02035-2
100ul

Human DSG2 ELISA Kit PicoKine®

Human

ELISA

$499
Cat # EK2189
96 wells/kit, with removable strips.

Desmoglein 2 (DSG2) (NM_001943) Human Over-expression Lysate

Human

$628
Cat # LS001829
100 µg

Anti-Desmoglein 2/DSG2 Antibody Picoband® (monoclonal, 2B4D1)

Human

IHC, WB

$370
Cat # M02035-2
100 μg/vial

DSG2 Overview

Facts about Desmoglein-2.

DSG2 3D structure. Source: alphafold

Desmoglein-2 (DSG2)

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

Gene Information

Human
Gene Name:	DSG2
Uniprot:	Q14126
Entrez:	1829

Family

Belongs to:

No superfamily

Alternative Names

ARVC10; ARVD10; Cadherin family member 5; CDHF5; CDHF5MGC117034; CMD1BB; desmoglein 2; Desmoglein2; Desmoglein-2; DSG2; HDGC; MGC117036; MGC117037

Molecular Weight

Mass (kDA):
122.294 kDA

Genomic Context


Human

Location:	18q12.1
Sequence:	18; NC_000018.10 (31498177..31549008)

Tissue Specificity

All of the tissues tested and carcinomas.

Subcellular Localizations

Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.

Diseases

Tissue Adhesions
Arrhythmogenic Right Ventricular Dysplasia
Neoplasms
Cardiomyopathies
Malignant Neoplasms
Carcinoma
Cardiac Arrhythmia
Dental Plaque
Pemphigus Foliaceus
Neoplasm Metastasis
Malignant Squamous Cell Neoplasm
Sudden Death

Bulla
Skin Neoplasms
Malignant Paraganglionic Neoplasm
Cell Invasion
Sudden Cardiac Death
Dermatologic Disorders

Pathways

Cell Adhesion
Cell-cell Adhesion
Pathogenesis
Localization
Desmosome Assembly
Cell Proliferation
Cell Migration
Cell Death
Keratinization
Transport
Keratinocyte Differentiation
Inflammatory Response
Epithelial Cell-cell Adhesion

Hair Follicle Development
Programmed Cell Death
Proteolysis
Immune Response
Tropism
Epiboly
Spermatogenesis

PTMs

Cleavage

Phosphorylation

Oxidation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/DSG2

References

PMID: 8143788 by Schaefer S., et al. Identification of the ubiquitous human desmoglein, Dsg2, and the expression catalogue of the desmoglein subfamily of desmosomal cadherins.

PMID: 1935985 by Koch P.J., et al. Complete amino acid sequence of the epidermal desmoglein precursor polypeptide and identification of a second type of desmoglein gene.